The University of Southampton
University of Southampton Institutional Repository

Photoredox catalysed reductive cleavage of dibenzothiophene dioxides enabled by a temperature-controlled photoreactor

Photoredox catalysed reductive cleavage of dibenzothiophene dioxides enabled by a temperature-controlled photoreactor
Photoredox catalysed reductive cleavage of dibenzothiophene dioxides enabled by a temperature-controlled photoreactor
The cleavage of C–S bonds in dibenzothiophene dioxides under reductive photoredox catalysed conditions is reported. The reactions afford sulfinates, which can be used in a variety of subsequent transformations for diversification. When using unsymmetrical dibenzothiophene substrates, reductive cleavage occurs preferentially at one C–S bond. Experimental and computational studies provide insight into this interesting selectivity. The process tolerates the presence of oil (dodecane), highlighting a possible application in the removal of dibenzothiophene impurities from crude oil. The reactivity of some substrates is highly dependent on reaction temperature, hence the development of a versatile and inexpensive 3D printed photoreactor that allows for the precise control of reaction temperature is also reported.
1478-6524
Wang, Siyuan
146e7d4a-2178-405f-bb89-19871eb6d6b1
Le, Quang Truong
f992d90c-d3fb-4d33-b3fa-d5f07ea5a6f6
Shishido, Yoshiteru
f18611e1-eb0a-4bd9-9124-d3c5be898af6
Kokculer, Ismail Y.
b131f57c-ffbe-4184-9c01-77bc95123363
Yamazaki, Ken
6bd1ebc0-1530-46b4-bcf0-f07100d0e42e
Perry, Gregory J.P.
766e7fc8-abf3-4d1e-9949-c1b3439a2185
Nightingale, Adrian M.
43e02f81-7814-4159-a4ea-1456f4583556
Yorimitsu, Hideki
5790badd-1359-473d-b584-a4a57406574e
Wang, Siyuan
146e7d4a-2178-405f-bb89-19871eb6d6b1
Le, Quang Truong
f992d90c-d3fb-4d33-b3fa-d5f07ea5a6f6
Shishido, Yoshiteru
f18611e1-eb0a-4bd9-9124-d3c5be898af6
Kokculer, Ismail Y.
b131f57c-ffbe-4184-9c01-77bc95123363
Yamazaki, Ken
6bd1ebc0-1530-46b4-bcf0-f07100d0e42e
Perry, Gregory J.P.
766e7fc8-abf3-4d1e-9949-c1b3439a2185
Nightingale, Adrian M.
43e02f81-7814-4159-a4ea-1456f4583556
Yorimitsu, Hideki
5790badd-1359-473d-b584-a4a57406574e

Wang, Siyuan, Le, Quang Truong, Shishido, Yoshiteru, Kokculer, Ismail Y., Yamazaki, Ken, Perry, Gregory J.P., Nightingale, Adrian M. and Yorimitsu, Hideki (2025) Photoredox catalysed reductive cleavage of dibenzothiophene dioxides enabled by a temperature-controlled photoreactor. Chemical Science. (doi:10.1039/D5SC05889A).

Record type: Article

Abstract

The cleavage of C–S bonds in dibenzothiophene dioxides under reductive photoredox catalysed conditions is reported. The reactions afford sulfinates, which can be used in a variety of subsequent transformations for diversification. When using unsymmetrical dibenzothiophene substrates, reductive cleavage occurs preferentially at one C–S bond. Experimental and computational studies provide insight into this interesting selectivity. The process tolerates the presence of oil (dodecane), highlighting a possible application in the removal of dibenzothiophene impurities from crude oil. The reactivity of some substrates is highly dependent on reaction temperature, hence the development of a versatile and inexpensive 3D printed photoreactor that allows for the precise control of reaction temperature is also reported.

Text
ChemSci_SW_251020_Pure - Accepted Manuscript
Download (879kB)
Text
d5sc05889a - Version of Record
Available under License Creative Commons Attribution.
Download (2MB)

More information

Accepted/In Press date: 22 October 2025
e-pub ahead of print date: 23 October 2025

Identifiers

Local EPrints ID: 507275
URI: http://eprints.soton.ac.uk/id/eprint/507275
ISSN: 1478-6524
PURE UUID: 040a3da8-def8-4bfa-afb2-491bcd40cf69
ORCID for Gregory J.P. Perry: ORCID iD orcid.org/0000-0001-8173-3369

Catalogue record

Date deposited: 02 Dec 2025 18:12
Last modified: 03 Dec 2025 03:05

Export record

Altmetrics

Contributors

Author: Siyuan Wang
Author: Quang Truong Le
Author: Yoshiteru Shishido
Author: Ismail Y. Kokculer
Author: Ken Yamazaki
Author: Gregory J.P. Perry ORCID iD
Author: Adrian M. Nightingale
Author: Hideki Yorimitsu

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×