Anaphylaxis following single component measles and rubella immunisation
Anaphylaxis following single component measles and rubella immunisation
Anaphylaxis as an adverse event following immunisation (AEFI) is a rare occurrence. We report four cases of anaphylaxis following administration of single component measles or rubella vaccine between January 2003 and June 2007. We estimate that the incidence of anaphylaxis to measles and rubella single component vaccines is 18.9 and 22.4 cases/100 000 doses, respectively. These figures are likely to be an underestimate but are higher than expected. Our calculations were hampered by lack of immunisation reporting data from the private sector. We recommend that NHS standards of vaccine data reporting are also applied to private clinics.
974-975
Erlewyn-Lajeunesse, M.
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Manek, R.
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Lingam, R.
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Finn, A.
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Emond, A.
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Erlewyn-Lajeunesse, M.
e1763b6d-165b-45c5-9108-5dc8722220b9
Manek, R.
d5f4227d-34ce-4732-ab9f-9a5184499bab
Lingam, R.
b3c84c11-93cb-4c62-bf07-29782c936f41
Finn, A.
51e100d7-bd49-442f-b50d-240841fa25f0
Emond, A.
54bf4dc8-d586-4a4a-8244-816af7f32255
Erlewyn-Lajeunesse, M., Manek, R., Lingam, R., Finn, A. and Emond, A.
(2008)
Anaphylaxis following single component measles and rubella immunisation.
Archives of Disease in Childhood, 93 (11), .
(doi:10.1136/adc.2008.138289).
Abstract
Anaphylaxis as an adverse event following immunisation (AEFI) is a rare occurrence. We report four cases of anaphylaxis following administration of single component measles or rubella vaccine between January 2003 and June 2007. We estimate that the incidence of anaphylaxis to measles and rubella single component vaccines is 18.9 and 22.4 cases/100 000 doses, respectively. These figures are likely to be an underestimate but are higher than expected. Our calculations were hampered by lack of immunisation reporting data from the private sector. We recommend that NHS standards of vaccine data reporting are also applied to private clinics.
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Accepted/In Press date: 2 June 2008
e-pub ahead of print date: 21 October 2008
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Local EPrints ID: 508033
URI: http://eprints.soton.ac.uk/id/eprint/508033
ISSN: 0003-9888
PURE UUID: 682f523f-46a0-4cc6-a7f3-62eb4eccf7d2
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Date deposited: 12 Jan 2026 17:36
Last modified: 17 Jan 2026 03:14
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Author:
M. Erlewyn-Lajeunesse
Author:
R. Manek
Author:
R. Lingam
Author:
A. Finn
Author:
A. Emond
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