When more is not worse: genetic subtypes of obesity challenge conventional risk paradigms
When more is not worse: genetic subtypes of obesity challenge conventional risk paradigms
Emerging evidence challenges the view of obesity as a uniform metabolic risk. Spotlighting the recent Nature Medicine study by Chami et al., this piece discusses how "uncoupling" adiposity from its cardiometabolic consequences reveals biologically distinct subtypes of obesity. Integrating imaging and multi-omics offers a promising path toward personalized obesity management and deeper mechanistic insight.
2099-2101
Yaghootkar, Hanieh
e45e4357-2f42-4eeb-a01a-18b7d3a00518
4 November 2025
Yaghootkar, Hanieh
e45e4357-2f42-4eeb-a01a-18b7d3a00518
Yaghootkar, Hanieh
(2025)
When more is not worse: genetic subtypes of obesity challenge conventional risk paradigms.
Cell Metabolism, 37 (11), .
(doi:10.1016/j.cmet.2025.10.002).
Abstract
Emerging evidence challenges the view of obesity as a uniform metabolic risk. Spotlighting the recent Nature Medicine study by Chami et al., this piece discusses how "uncoupling" adiposity from its cardiometabolic consequences reveals biologically distinct subtypes of obesity. Integrating imaging and multi-omics offers a promising path toward personalized obesity management and deeper mechanistic insight.
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Obesity_subTypes_CellMetabolism_2Oct25_HY
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e-pub ahead of print date: 4 November 2025
Published date: 4 November 2025
Identifiers
Local EPrints ID: 508133
URI: http://eprints.soton.ac.uk/id/eprint/508133
ISSN: 1550-4131
PURE UUID: 08f7d14e-273d-4661-8819-06accb1f557c
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Date deposited: 13 Jan 2026 18:03
Last modified: 14 Jan 2026 03:13
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Author:
Hanieh Yaghootkar
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