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Avelumab with axitinib for untreated advanced renal cell carcinoma (MA review of TA645)

Avelumab with axitinib for untreated advanced renal cell carcinoma (MA review of TA645)
Avelumab with axitinib for untreated advanced renal cell carcinoma (MA review of TA645)
This report is a critique of the company’s submission (CS) to NICE from Merck on the clinical effectiveness and cost effectiveness of avelumab (Bavencio) in combination with axitinib (Inlyta) for treating adults with untreated advanced renal cell carcinoma (aRCC). It identifies the strengths and weakness of the CS.
Southampton Health Technology Assessments Centre
Hawa, Asyl
64ce4257-6176-4a4e-bce5-5e1147377355
Picot, Jo
324d6f20-a105-49fd-9fb0-88791be84ada
Woods, Lois
8149aa11-7664-4052-a18b-98f7bde83180
Ribeiro, Ines
2fd1901b-61bd-4ad5-81b3-a3f8145ec144
Lord, Joanne
fd3b2bf0-9403-466a-8184-9303bdc80a9a
Hawa, Asyl
64ce4257-6176-4a4e-bce5-5e1147377355
Picot, Jo
324d6f20-a105-49fd-9fb0-88791be84ada
Woods, Lois
8149aa11-7664-4052-a18b-98f7bde83180
Ribeiro, Ines
2fd1901b-61bd-4ad5-81b3-a3f8145ec144
Lord, Joanne
fd3b2bf0-9403-466a-8184-9303bdc80a9a

Hawa, Asyl, Picot, Jo, Woods, Lois, Ribeiro, Ines and Lord, Joanne (2026) Avelumab with axitinib for untreated advanced renal cell carcinoma (MA review of TA645) Southampton Health Technology Assessments Centre 121pp.

Record type: Monograph (Project Report)

Abstract

This report is a critique of the company’s submission (CS) to NICE from Merck on the clinical effectiveness and cost effectiveness of avelumab (Bavencio) in combination with axitinib (Inlyta) for treating adults with untreated advanced renal cell carcinoma (aRCC). It identifies the strengths and weakness of the CS.

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Avelumab EAG report - Version of Record
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Published date: 8 January 2026

Identifiers

Local EPrints ID: 508324
URI: http://eprints.soton.ac.uk/id/eprint/508324
PURE UUID: cbe7c38d-fe7d-48fd-ada2-351f9d4550be
ORCID for Asyl Hawa: ORCID iD orcid.org/0000-0002-2270-1057
ORCID for Jo Picot: ORCID iD orcid.org/0000-0001-5987-996X
ORCID for Lois Woods: ORCID iD orcid.org/0000-0002-4587-9149
ORCID for Ines Ribeiro: ORCID iD orcid.org/0000-0001-8464-4513
ORCID for Joanne Lord: ORCID iD orcid.org/0000-0003-1086-1624

Catalogue record

Date deposited: 16 Jan 2026 18:39
Last modified: 17 Jan 2026 03:20

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Contributors

Author: Asyl Hawa ORCID iD
Author: Jo Picot ORCID iD
Author: Lois Woods ORCID iD
Author: Ines Ribeiro ORCID iD
Author: Joanne Lord ORCID iD

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