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The measurement of functioning as an outcome in intervention studies targeting intrusive memories of trauma: a narrative review

The measurement of functioning as an outcome in intervention studies targeting intrusive memories of trauma: a narrative review
The measurement of functioning as an outcome in intervention studies targeting intrusive memories of trauma: a narrative review

There has been a call for innovative, low-cost and simple treatments for people who have experienced trauma. The proposal that targeting intrusive memories could have the downstream effect of reducing other posttrauma symptoms or preventing their emergence has prompted the development of single-symptom interventions for intrusive memories, drawing on cognitive neuroscience models of memory consolidation and reconsolidation. To understand their full therapeutic impact, evaluations of the effectiveness of single-symptom interventions should include measures of broad outcomes (i.e. functioning), in addition to intrusion-related measures. This narrative review examined whether intervention studies targeting intrusive memories after real-world trauma measured functioning as an outcome, and if so, how. Twenty-five studies were included, 17 of which included a measure of functioning. Functional outcomes were not consistently measured in a rigorous or informative way. We make recommendations to address these issues and propose ways in which functioning can be effectively assessed in future work.

Cognitive neuroscience, Functioning, Intrusive memory, Measurement, Single-symptom intervention, Trauma
3059-3042
148-182
Greenfield, Emily M.
3b0d883a-59ad-4469-aaaa-621326b6fe6a
Mason, Oliver J.
b9611d2d-5be0-439c-8ef0-7ed7c7156e3c
Holmes, Emily A.
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Young, Kerry
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Moulds, Michelle L.
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Greenfield, Emily M.
3b0d883a-59ad-4469-aaaa-621326b6fe6a
Mason, Oliver J.
b9611d2d-5be0-439c-8ef0-7ed7c7156e3c
Holmes, Emily A.
a6379ab3-b182-45f8-87c9-3e07e90fe469
Young, Kerry
738e5fba-8e09-4c83-8cd1-d0bbb745d8bb
Moulds, Michelle L.
df022906-d599-4e2f-933a-7e0b292214d4

Greenfield, Emily M., Mason, Oliver J., Holmes, Emily A., Young, Kerry and Moulds, Michelle L. (2025) The measurement of functioning as an outcome in intervention studies targeting intrusive memories of trauma: a narrative review. International Journal of Cognitive Behavioral Therapy, 18 (1), 148-182. (doi:10.1007/s41811-025-00241-8).

Record type: Article

Abstract

There has been a call for innovative, low-cost and simple treatments for people who have experienced trauma. The proposal that targeting intrusive memories could have the downstream effect of reducing other posttrauma symptoms or preventing their emergence has prompted the development of single-symptom interventions for intrusive memories, drawing on cognitive neuroscience models of memory consolidation and reconsolidation. To understand their full therapeutic impact, evaluations of the effectiveness of single-symptom interventions should include measures of broad outcomes (i.e. functioning), in addition to intrusion-related measures. This narrative review examined whether intervention studies targeting intrusive memories after real-world trauma measured functioning as an outcome, and if so, how. Twenty-five studies were included, 17 of which included a measure of functioning. Functional outcomes were not consistently measured in a rigorous or informative way. We make recommendations to address these issues and propose ways in which functioning can be effectively assessed in future work.

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Accepted/In Press date: 29 October 2024
e-pub ahead of print date: 19 February 2025
Published date: March 2025
Keywords: Cognitive neuroscience, Functioning, Intrusive memory, Measurement, Single-symptom intervention, Trauma

Identifiers

Local EPrints ID: 509490
URI: http://eprints.soton.ac.uk/id/eprint/509490
ISSN: 3059-3042
PURE UUID: c1103df8-67f7-4de3-894c-a00821effad8
ORCID for Emily A. Holmes: ORCID iD orcid.org/0000-0001-7319-3112

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Date deposited: 24 Feb 2026 17:45
Last modified: 07 Mar 2026 04:26

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Contributors

Author: Emily M. Greenfield
Author: Oliver J. Mason
Author: Emily A. Holmes ORCID iD
Author: Kerry Young
Author: Michelle L. Moulds

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