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Just-in-case medication use by ambulance paramedics responding to end-of-life care in the community: protocol for a multi-method study (RELIEF)

Just-in-case medication use by ambulance paramedics responding to end-of-life care in the community: protocol for a multi-method study (RELIEF)
Just-in-case medication use by ambulance paramedics responding to end-of-life care in the community: protocol for a multi-method study (RELIEF)
Introduction: at the end of life, anticipatory or just-in-case (JIC) medications may help manage patients’ symptoms. Sometimes, emergency ambulances attend patients for whom JIC medications have not been prescribed. In Wales, UK, a Welsh Ambulance Services University NHS Trust (WAST) JIC intervention was launched in May 2020 in response to COVID-19, to enable ambulance paramedics to administer JIC medications to patients for whom they had not previously been prescribed. The ambulance JIC intervention is an ongoing feature of WAST pre-hospital care but has received limited evaluation. This study will explore the rationale, usage, costs and views of stakeholders of the WAST JIC medications intervention.

Methods: we will employ a multi-method observational study design that incorporates both quantitative and qualitative aspects, informed by implementation science. We will prepare a detailed description of the WAST JIC medications intervention, its rationale and its use. We will interview paramedics and doctors who have provided the intervention, as well as paid and informal carers who were present during the care episode. We will also hold a focus group with paramedics who have not administered the intervention and undertake a cost analysis to estimate costs and savings associated with the intervention. We will use descriptive statistics to analyse quantitative data and a framework approach for qualitative data.

Conclusion: this study, which focuses on the voices of patient advocates and practitioners, has the potential to shape future provision of this and similar services in WAST and other care providers.
1478-4726
Moore, Chris
7258c4a5-1940-4d08-b4aa-803b89724882
Kingston, Mark
ef910a6b-38d5-40dc-a2da-b393e4f16186
Baker, Idris
084f13e8-031a-41b1-bcd4-0c725205d6ce
Campling, Natasha
0e0410b0-a9cd-486d-a51f-20d80df04791
Hills, Marika
5e6f1838-8c14-423b-aa3f-ada7013f20c4
Jones, Emyr
c154fa05-b038-4c83-9cd3-e5fa037ec4d8
Jones, Sian
7d683fdf-2b87-4776-bf57-ef12b399e507
Kumar, Rashmi
3d5593e9-97ef-431a-afbd-f3e68aa823a8
O'Brian, Edward
22a62441-e1a8-4e4a-9544-0d7b0ad85a24
Porter, Alison
12d7b83a-ce50-4b5c-9953-bf5a2c582b85
Sewell, Bernadette
2de83873-3953-43be-8a0b-f76a583572e7
Williams, Lauren
4133a96e-6892-4b5b-9baa-d10dc2a8552b
Xanthe, Cendl
5d217818-01e4-42bf-8e79-ed136a17aa73
Moore, Chris
7258c4a5-1940-4d08-b4aa-803b89724882
Kingston, Mark
ef910a6b-38d5-40dc-a2da-b393e4f16186
Baker, Idris
084f13e8-031a-41b1-bcd4-0c725205d6ce
Campling, Natasha
0e0410b0-a9cd-486d-a51f-20d80df04791
Hills, Marika
5e6f1838-8c14-423b-aa3f-ada7013f20c4
Jones, Emyr
c154fa05-b038-4c83-9cd3-e5fa037ec4d8
Jones, Sian
7d683fdf-2b87-4776-bf57-ef12b399e507
Kumar, Rashmi
3d5593e9-97ef-431a-afbd-f3e68aa823a8
O'Brian, Edward
22a62441-e1a8-4e4a-9544-0d7b0ad85a24
Porter, Alison
12d7b83a-ce50-4b5c-9953-bf5a2c582b85
Sewell, Bernadette
2de83873-3953-43be-8a0b-f76a583572e7
Williams, Lauren
4133a96e-6892-4b5b-9baa-d10dc2a8552b
Xanthe, Cendl
5d217818-01e4-42bf-8e79-ed136a17aa73

Moore, Chris, Kingston, Mark, Baker, Idris, Campling, Natasha, Hills, Marika, Jones, Emyr, Jones, Sian, Kumar, Rashmi, O'Brian, Edward, Porter, Alison, Sewell, Bernadette, Williams, Lauren and Xanthe, Cendl (2025) Just-in-case medication use by ambulance paramedics responding to end-of-life care in the community: protocol for a multi-method study (RELIEF). British Paramedic Journal, 10 (3). (doi:10.29045/14784726.2025.12.10.3.1).

Record type: Article

Abstract

Introduction: at the end of life, anticipatory or just-in-case (JIC) medications may help manage patients’ symptoms. Sometimes, emergency ambulances attend patients for whom JIC medications have not been prescribed. In Wales, UK, a Welsh Ambulance Services University NHS Trust (WAST) JIC intervention was launched in May 2020 in response to COVID-19, to enable ambulance paramedics to administer JIC medications to patients for whom they had not previously been prescribed. The ambulance JIC intervention is an ongoing feature of WAST pre-hospital care but has received limited evaluation. This study will explore the rationale, usage, costs and views of stakeholders of the WAST JIC medications intervention.

Methods: we will employ a multi-method observational study design that incorporates both quantitative and qualitative aspects, informed by implementation science. We will prepare a detailed description of the WAST JIC medications intervention, its rationale and its use. We will interview paramedics and doctors who have provided the intervention, as well as paid and informal carers who were present during the care episode. We will also hold a focus group with paramedics who have not administered the intervention and undertake a cost analysis to estimate costs and savings associated with the intervention. We will use descriptive statistics to analyse quantitative data and a framework approach for qualitative data.

Conclusion: this study, which focuses on the voices of patient advocates and practitioners, has the potential to shape future provision of this and similar services in WAST and other care providers.

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e-pub ahead of print date: 1 December 2025
Published date: 1 December 2025

Identifiers

Local EPrints ID: 511412
URI: http://eprints.soton.ac.uk/id/eprint/511412
ISSN: 1478-4726
PURE UUID: f6d23a9e-413f-4f36-a807-269bc934e963
ORCID for Natasha Campling: ORCID iD orcid.org/0000-0002-4158-7894

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Date deposited: 14 May 2026 16:31
Last modified: 15 May 2026 01:48

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Contributors

Author: Chris Moore
Author: Mark Kingston
Author: Idris Baker
Author: Marika Hills
Author: Emyr Jones
Author: Sian Jones
Author: Rashmi Kumar
Author: Edward O'Brian
Author: Alison Porter
Author: Bernadette Sewell
Author: Lauren Williams
Author: Cendl Xanthe

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