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Preterm infants: immunity and immunisation

Preterm infants: immunity and immunisation
Preterm infants: immunity and immunisation
Preterm birth affects around 7–8% of pregnancies in the UK. There are immunological consequences of preterm birth, epidemiological differences in infectious diseases in the preterm population and differences in immunity after vaccination, both following immunisations received in pregnancy and following vaccines administered to infants themselves. There are also often increased concerns about the side effects experienced by preterm infants following vaccination. It is important that health care professionals and parents are fully informed about the specific issues of vaccination in this group.

1359-2998
Calvert, Anna
03bc971b-ed4f-4c6c-bcb5-29943bff1661
Shaw, Emily
31157e86-268e-4602-bd15-39ee9c63aaa6
Jones, Christine E.
48229079-8b58-4dcb-8374-d9481fe7b426
Le Doare, Kirsty
9424dc5c-4484-41d3-86dd-29cfaffb43f5
Heath, Paul T
fce44186-c98d-4bdf-8d60-d0f89fff2ce9
Calvert, Anna
03bc971b-ed4f-4c6c-bcb5-29943bff1661
Shaw, Emily
31157e86-268e-4602-bd15-39ee9c63aaa6
Jones, Christine E.
48229079-8b58-4dcb-8374-d9481fe7b426
Le Doare, Kirsty
9424dc5c-4484-41d3-86dd-29cfaffb43f5
Heath, Paul T
fce44186-c98d-4bdf-8d60-d0f89fff2ce9

Calvert, Anna, Shaw, Emily, Jones, Christine E., Le Doare, Kirsty and Heath, Paul T (2026) Preterm infants: immunity and immunisation. Archives of Disease in Childhood: Fetal and Neonatal Edition. (doi:10.1136/archdischild-2024-327480).

Record type: Review

Abstract

Preterm birth affects around 7–8% of pregnancies in the UK. There are immunological consequences of preterm birth, epidemiological differences in infectious diseases in the preterm population and differences in immunity after vaccination, both following immunisations received in pregnancy and following vaccines administered to infants themselves. There are also often increased concerns about the side effects experienced by preterm infants following vaccination. It is important that health care professionals and parents are fully informed about the specific issues of vaccination in this group.

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ADC_paper_final_version_for_resubmission_January 2026_final amendments_clean - Accepted Manuscript
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e-pub ahead of print date: 26 February 2026

Identifiers

Local EPrints ID: 511631
URI: http://eprints.soton.ac.uk/id/eprint/511631
ISSN: 1359-2998
PURE UUID: 175bd8e3-870b-414e-bc1e-721cca8dfc7e
ORCID for Christine E. Jones: ORCID iD orcid.org/0000-0003-1523-2368

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Date deposited: 26 May 2026 16:37
Last modified: 27 May 2026 01:52

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Contributors

Author: Anna Calvert
Author: Emily Shaw
Author: Kirsty Le Doare
Author: Paul T Heath

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