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Emerging directions in tauopathy research

Emerging directions in tauopathy research
Emerging directions in tauopathy research
The Tau Global Conference 2025, hosted by the Alzheimer’s Association, CurePSP, and the Rainwater Charitable Foundation, convened international experts from academia, industry, government, and philanthropy to explore advances and challenges in tauopathy research. The meeting highlighted progress across tau biology, including emerging models of tau regulation, degradation, and propagation; advances in biomarker development for the diagnosis andstaging of tauopathies; and evolving therapeutic strategies targeting diverse aspects of tau pathophysiology. Discussions also emphasized the importance of cross-sector collaboration, and global initiatives to address disparities in tau research. This report synthesizes key insights from the conference and underscores the critical role of interdisciplinary, biomarker-driven, andglobally inclusive approaches in accelerating the translation of tau research into effective clinical applications.
1552-5260
Buree, Luc
a745b9b6-eb8b-449b-a211-b836589c428b
Wildsmith, Kristin
091b134c-1c44-4f3f-aaba-fff26786be59
Alladi, Survarna
13407383-23c5-4beb-8c13-32a93995e368
Boche, Delphine
bdcca10e-6302-4dd0-919f-67218f7e0d61
et al.
Buree, Luc
a745b9b6-eb8b-449b-a211-b836589c428b
Wildsmith, Kristin
091b134c-1c44-4f3f-aaba-fff26786be59
Alladi, Survarna
13407383-23c5-4beb-8c13-32a93995e368
Boche, Delphine
bdcca10e-6302-4dd0-919f-67218f7e0d61

Buree, Luc, Wildsmith, Kristin and Alladi, Survarna , et al. (2026) Emerging directions in tauopathy research. Alzheimer's & Dementia, [ADJ-D-26-00255R1]. (In Press)

Record type: Review

Abstract

The Tau Global Conference 2025, hosted by the Alzheimer’s Association, CurePSP, and the Rainwater Charitable Foundation, convened international experts from academia, industry, government, and philanthropy to explore advances and challenges in tauopathy research. The meeting highlighted progress across tau biology, including emerging models of tau regulation, degradation, and propagation; advances in biomarker development for the diagnosis andstaging of tauopathies; and evolving therapeutic strategies targeting diverse aspects of tau pathophysiology. Discussions also emphasized the importance of cross-sector collaboration, and global initiatives to address disparities in tau research. This report synthesizes key insights from the conference and underscores the critical role of interdisciplinary, biomarker-driven, andglobally inclusive approaches in accelerating the translation of tau research into effective clinical applications.

Text
ADJ-D-26-00255_R1 - Accepted Manuscript
Restricted to Repository staff only until 28 June 2026.
Available under License Creative Commons Attribution.
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More information

Accepted/In Press date: 1 April 2026

Identifiers

Local EPrints ID: 511693
URI: http://eprints.soton.ac.uk/id/eprint/511693
ISSN: 1552-5260
PURE UUID: 28e0e9cc-1be7-4e10-ad3b-c86bef167ec7
ORCID for Delphine Boche: ORCID iD orcid.org/0000-0002-5884-130X

Catalogue record

Date deposited: 28 May 2026 16:35
Last modified: 29 May 2026 01:38

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Contributors

Author: Luc Buree
Author: Kristin Wildsmith
Author: Survarna Alladi
Author: Delphine Boche ORCID iD
Corporate Author: et al.

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