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Optofluidic integration for microanalysis

Optofluidic integration for microanalysis
Optofluidic integration for microanalysis
This review describes recent research in the application of optical techniques to microfluidic systems for chemical and biochemical analysis. The "lab-on-a-chip" presents great benefits in terms of reagent and sample consumption, speed, precision, and automation of analysis, and thus cost and ease of use, resulting in rapidly escalating adoption of microfluidic approaches. The use of light for detection of particles and chemical species within these systems is widespread because of the sensitivity and specificity which can be achieved, and optical trapping, manipulation and sorting of particles show significant benefits in terms of discrimination and reconfigurability. Nonetheless, the full integration of optical functions within microfluidic chips is in its infancy, and this review aims to highlight approaches which may contribute to further miniaturisation and integration.
lab-on-a-chip, microfluidics, optical detection, optical trapping, Integrated optics, optofluidics
1613-4982
53-79
Hunt, Hamish C.
b58afe40-9102-4a47-8d81-1fdd5463f4fe
Wilkinson, James S.
73483cf3-d9f2-4688-9b09-1c84257884ca
Hunt, Hamish C.
b58afe40-9102-4a47-8d81-1fdd5463f4fe
Wilkinson, James S.
73483cf3-d9f2-4688-9b09-1c84257884ca

Hunt, Hamish C. and Wilkinson, James S. (2008) Optofluidic integration for microanalysis. Microfluidics and Nanofluidics, 4 (1-2), 53-79. (doi:10.1007/s10404-007-0223-y).

Record type: Article

Abstract

This review describes recent research in the application of optical techniques to microfluidic systems for chemical and biochemical analysis. The "lab-on-a-chip" presents great benefits in terms of reagent and sample consumption, speed, precision, and automation of analysis, and thus cost and ease of use, resulting in rapidly escalating adoption of microfluidic approaches. The use of light for detection of particles and chemical species within these systems is widespread because of the sensitivity and specificity which can be achieved, and optical trapping, manipulation and sorting of particles show significant benefits in terms of discrimination and reconfigurability. Nonetheless, the full integration of optical functions within microfluidic chips is in its infancy, and this review aims to highlight approaches which may contribute to further miniaturisation and integration.

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Published date: January 2008
Keywords: lab-on-a-chip, microfluidics, optical detection, optical trapping, Integrated optics, optofluidics

Identifiers

Local EPrints ID: 52054
URI: http://eprints.soton.ac.uk/id/eprint/52054
ISSN: 1613-4982
PURE UUID: 754a5c1a-42c1-45d9-82e1-1d3c40746ae7
ORCID for James S. Wilkinson: ORCID iD orcid.org/0000-0003-4712-1697

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Date deposited: 09 Jun 2008
Last modified: 16 Mar 2024 02:33

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Contributors

Author: Hamish C. Hunt

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