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Synthesis of optically pure 4-hydroxymethyl-3-phenoxy-2-azetidinone from D-glucal

Synthesis of optically pure 4-hydroxymethyl-3-phenoxy-2-azetidinone from D-glucal
Synthesis of optically pure 4-hydroxymethyl-3-phenoxy-2-azetidinone from D-glucal
A convenient approach to enantiomerically pure 4-hydroxymethyl- 3-phenoxy-2-azetidinone has been carried out using the easily available aldehyde 5 as chiral starting material.
staudinger reaction, beta-lactam, ozonolysis, beta-lactams, chiral auxiliary, asymmetric-synthesis, carbohydrate
1881-0942
857-862
Areces, P.
e88f0d0f-33ff-4e7a-8839-c6237abf795e
Carrasco, E.
2351eaf8-a83e-476f-99fc-a3601ec5949c
Monterde, M.
13e4d0de-54d5-4c57-997b-04a655e1b38d
Light, M.E.
cf57314e-6856-491b-a8d2-2dffc452e161
Plumet, J.
9709c2cf-1cd0-4ba0-b982-a18212bb560f
Areces, P.
e88f0d0f-33ff-4e7a-8839-c6237abf795e
Carrasco, E.
2351eaf8-a83e-476f-99fc-a3601ec5949c
Monterde, M.
13e4d0de-54d5-4c57-997b-04a655e1b38d
Light, M.E.
cf57314e-6856-491b-a8d2-2dffc452e161
Plumet, J.
9709c2cf-1cd0-4ba0-b982-a18212bb560f

Areces, P., Carrasco, E., Monterde, M., Light, M.E. and Plumet, J. (2007) Synthesis of optically pure 4-hydroxymethyl-3-phenoxy-2-azetidinone from D-glucal. Heterocycles, 73 (1), 857-862.

Record type: Article

Abstract

A convenient approach to enantiomerically pure 4-hydroxymethyl- 3-phenoxy-2-azetidinone has been carried out using the easily available aldehyde 5 as chiral starting material.

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More information

Published date: 2007
Keywords: staudinger reaction, beta-lactam, ozonolysis, beta-lactams, chiral auxiliary, asymmetric-synthesis, carbohydrate

Identifiers

Local EPrints ID: 54237
URI: http://eprints.soton.ac.uk/id/eprint/54237
ISSN: 1881-0942
PURE UUID: 7d9430e4-d810-4b09-9948-76e30382e711
ORCID for M.E. Light: ORCID iD orcid.org/0000-0002-0585-0843

Catalogue record

Date deposited: 31 Jul 2008
Last modified: 09 Jan 2022 02:59

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Contributors

Author: P. Areces
Author: E. Carrasco
Author: M. Monterde
Author: M.E. Light ORCID iD
Author: J. Plumet

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