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2 '-O-dimethylaminoethoxyuridine and 5-dimethylaminopropargyl deoxyuridine for at base pair recognition in triple helices

2 '-O-dimethylaminoethoxyuridine and 5-dimethylaminopropargyl deoxyuridine for at base pair recognition in triple helices
2 '-O-dimethylaminoethoxyuridine and 5-dimethylaminopropargyl deoxyuridine for at base pair recognition in triple helices
The nucleoside analogues 2'-O-dimethylaminoethoxy uridine and 5-dimethylaminopropargyl deoxyuridine have been synthesised and incorporated into oligonucleotides. Their triplex-stabilising properties have been determined in fluorescence melting experiments.
antigene, triple helices, triplexes, at recognition
1525-7770
1283-1286
Brennan, Lavinia
bbf2c574-d0aa-469f-b7c2-04eac8ee660a
Peng, Guomei
815906fe-23a8-43aa-a1d0-316dff95369a
Srinivasan, Natarajan
d853c4c5-da37-4a46-b102-9bb285812d32
Fox, Keith R.
9da5debc-4e45-473e-ab8c-550d1104659f
Brown, Tom
a64aae36-bb30-42df-88a2-11be394e8c89
Brennan, Lavinia
bbf2c574-d0aa-469f-b7c2-04eac8ee660a
Peng, Guomei
815906fe-23a8-43aa-a1d0-316dff95369a
Srinivasan, Natarajan
d853c4c5-da37-4a46-b102-9bb285812d32
Fox, Keith R.
9da5debc-4e45-473e-ab8c-550d1104659f
Brown, Tom
a64aae36-bb30-42df-88a2-11be394e8c89

Brennan, Lavinia, Peng, Guomei, Srinivasan, Natarajan, Fox, Keith R. and Brown, Tom (2007) 2 '-O-dimethylaminoethoxyuridine and 5-dimethylaminopropargyl deoxyuridine for at base pair recognition in triple helices. Nucleosides, Nucleotides & Nucleic Acids, 26 (10-12), 1283-1286. (doi:10.1080/15257770701530525).

Record type: Article

Abstract

The nucleoside analogues 2'-O-dimethylaminoethoxy uridine and 5-dimethylaminopropargyl deoxyuridine have been synthesised and incorporated into oligonucleotides. Their triplex-stabilising properties have been determined in fluorescence melting experiments.

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More information

Published date: October 2007
Keywords: antigene, triple helices, triplexes, at recognition
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Identifiers

Local EPrints ID: 54252
URI: http://eprints.soton.ac.uk/id/eprint/54252
DOI: doi:10.1080/15257770701530525
ISSN: 1525-7770
PURE UUID: d9b4ff12-9c7f-411b-9857-cfb66900c112
ORCID for Keith R. Fox: ORCID iD orcid.org/0000-0002-2925-7315

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Date deposited: 30 Jul 2008
Last modified: 16 Mar 2024 02:36

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Contributors

Author: Lavinia Brennan
Author: Guomei Peng
Author: Natarajan Srinivasan
Author: Keith R. Fox ORCID iD
Author: Tom Brown

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