Synthesis of anthraquinone oligonucleotides for triplex stabilization


Zhao, Zhengyun, Peng, Guomei, Michels, Jan, Fox, Keith R. and Brown, Tom (2007) Synthesis of anthraquinone oligonucleotides for triplex stabilization Nucleosides, Nucleotides & Nucleic Acids, 26, (8 & 9), pp. 921-925. (doi:10.1080/15257770701506491).

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Description/Abstract

The synthesis of two anthraquinone phosphoramidites is described. In both cases the anthraquinone moiety is attached via a linker to the 5-position of a uracil base, allowing incorporation at any thymidine position in an oligonucleotide sequence. Anthraquinone-modified oligonucleotides have potential applications as triplex stabilizers and fluorescence quenchers.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1080/15257770701506491
ISSNs: 1525-7770 (print)
Keywords: anthraquinone, triplex stabilizers, fluorescence quenchers
Subjects:
ePrint ID: 54411
Date :
Date Event
August 2007Published
Date Deposited: 30 Jul 2008
Last Modified: 16 Apr 2017 17:47
Further Information:Google Scholar
URI: http://eprints.soton.ac.uk/id/eprint/54411

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