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Synthesis of anthraquinone oligonucleotides for triplex stabilization

Zhao, Zhengyun, Peng, Guomei, Michels, Jan, Fox, Keith R. and Brown, Tom (2007) Synthesis of anthraquinone oligonucleotides for triplex stabilization Nucleosides, Nucleotides & Nucleic Acids, 26, (8 & 9), pp. 921-925. (doi:10.1080/15257770701506491).

Record type: Article


The synthesis of two anthraquinone phosphoramidites is described. In both cases the anthraquinone moiety is attached via a linker to the 5-position of a uracil base, allowing incorporation at any thymidine position in an oligonucleotide sequence. Anthraquinone-modified oligonucleotides have potential applications as triplex stabilizers and fluorescence quenchers.

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Published date: August 2007
Keywords: anthraquinone, triplex stabilizers, fluorescence quenchers


Local EPrints ID: 54411
ISSN: 1525-7770
PURE UUID: f0642ab5-c7e6-469a-97e2-89e64f61f688
ORCID for Keith R. Fox: ORCID iD

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Date deposited: 30 Jul 2008
Last modified: 17 Jul 2017 14:35

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Author: Zhengyun Zhao
Author: Guomei Peng
Author: Jan Michels
Author: Keith R. Fox ORCID iD
Author: Tom Brown

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