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On the highly stereoselective addition of lithio-acetylides to alpha-hydroxy-ketones

Dunford, D., Guyader, M., Jones, S., Knight, D.W., Hursthouse, M.B. and Coles, S.J. (2008) On the highly stereoselective addition of lithio-acetylides to alpha-hydroxy-ketones Tetrahedron Letters, 49, (14), pp. 2240-2242. (doi:10.1016/j.tetlet.2008.02.032).

Record type: Article


Addition of 2 equiv of a lithio-acetylide to an unprotected ?-hydroxy ketone is extremely stereoselective in examples where the two ketone substituents are relatively large.

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Published date: 31 March 2008
Keywords: 5-endo-dig cyclizations, beta-iodofurans


Local EPrints ID: 54445
ISSN: 0040-4039
PURE UUID: dfbf8123-b902-44c2-a035-ae3b1a999b1e
ORCID for S.J. Coles: ORCID iD

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Date deposited: 05 Aug 2008
Last modified: 17 Jul 2017 14:35

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Author: D. Dunford
Author: M. Guyader
Author: S. Jones
Author: D.W. Knight
Author: M.B. Hursthouse
Author: S.J. Coles ORCID iD

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