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Long-acting medications for the hyperkinetic disorders A systematic review and European treatment guideline

Long-acting medications for the hyperkinetic disorders A systematic review and European treatment guideline
Long-acting medications for the hyperkinetic disorders A systematic review and European treatment guideline
A systematic review of published and unpublished data on the use of long-acting medications in ADHD and hyperkinetic disorder is reported, giving effect sizes and numbers-to-treat for extended-release stimulant preparations and atomoxetine (ATX). A panel of experts from several European countries used the review to make recommendations about the use of these drugs in practice, and conclusions are reported: (1) Long-acting preparations should be available and used; (2) They should not replace short-acting drugs (which will be the initial treatment for many children for reasons of cost and flexibility of dosing). Individual clinical choice is needed. (3) Both ATX and extended-release preparations of stimulants should be available. The choice will depend upon the circumstances, and detailed recommendations are made.
guidelines - review - stimulants - atomoxetine - ADHD
1018-8827
476-495
Banaschewski, Tobias
4627c589-04cc-4f5b-ac2d-05f547f63dfd
Coghill, David
deea8957-fdfc-488a-a3bb-fb9b536c7172
Santosh, Paramala
c1ac98e0-83b9-4583-a3ce-ca82085ffde4
Zuddas, Alessandro
51df7133-8494-4309-902d-bbf088341e46
Asherson, Philip
a734c1f6-f31a-450b-81c3-ba7bb373e147
Buitelaar, Jan
0a7a93a0-884f-4fe1-9cd8-6c9f9c5df4da
Danckaerts, Marina
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Döpfner, Manfred
cf7a4f00-b116-4d6f-8761-769ef42f1355
Faraone, Stephen. V.
11abe086-d301-4ca2-bbd5-d7a516be924f
Rothenberger, Aribert
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Sergeant, Joseph
9d13c879-0b3b-45df-8ba7-3978ca029ac5
Steinhausen, Hans-Christoph
991ad7f9-c5d1-4c61-8118-3d4895d2706d
Sonuga-Barke, Edmund.J.S.
bc80bf95-6cf9-4c76-a09d-eaaf0b717635
Taylor, Eric
0df56dc7-9553-44e2-9594-612d758f8684
Banaschewski, Tobias
4627c589-04cc-4f5b-ac2d-05f547f63dfd
Coghill, David
deea8957-fdfc-488a-a3bb-fb9b536c7172
Santosh, Paramala
c1ac98e0-83b9-4583-a3ce-ca82085ffde4
Zuddas, Alessandro
51df7133-8494-4309-902d-bbf088341e46
Asherson, Philip
a734c1f6-f31a-450b-81c3-ba7bb373e147
Buitelaar, Jan
0a7a93a0-884f-4fe1-9cd8-6c9f9c5df4da
Danckaerts, Marina
e7e7618b-6dd0-4520-bf4e-865597928758
Döpfner, Manfred
cf7a4f00-b116-4d6f-8761-769ef42f1355
Faraone, Stephen. V.
11abe086-d301-4ca2-bbd5-d7a516be924f
Rothenberger, Aribert
736981ca-a16d-44b3-8312-2067dc792a6d
Sergeant, Joseph
9d13c879-0b3b-45df-8ba7-3978ca029ac5
Steinhausen, Hans-Christoph
991ad7f9-c5d1-4c61-8118-3d4895d2706d
Sonuga-Barke, Edmund.J.S.
bc80bf95-6cf9-4c76-a09d-eaaf0b717635
Taylor, Eric
0df56dc7-9553-44e2-9594-612d758f8684

Banaschewski, Tobias, Coghill, David, Santosh, Paramala, Zuddas, Alessandro, Asherson, Philip, Buitelaar, Jan, Danckaerts, Marina, Döpfner, Manfred, Faraone, Stephen. V., Rothenberger, Aribert, Sergeant, Joseph, Steinhausen, Hans-Christoph, Sonuga-Barke, Edmund.J.S. and Taylor, Eric (2006) Long-acting medications for the hyperkinetic disorders A systematic review and European treatment guideline. European Child & Adolescent Psychiatry, 15 (8), 476-495. (doi:10.1007/s00787-006-0549-0).

Record type: Article

Abstract

A systematic review of published and unpublished data on the use of long-acting medications in ADHD and hyperkinetic disorder is reported, giving effect sizes and numbers-to-treat for extended-release stimulant preparations and atomoxetine (ATX). A panel of experts from several European countries used the review to make recommendations about the use of these drugs in practice, and conclusions are reported: (1) Long-acting preparations should be available and used; (2) They should not replace short-acting drugs (which will be the initial treatment for many children for reasons of cost and flexibility of dosing). Individual clinical choice is needed. (3) Both ATX and extended-release preparations of stimulants should be available. The choice will depend upon the circumstances, and detailed recommendations are made.

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Published date: December 2006
Keywords: guidelines - review - stimulants - atomoxetine - ADHD

Identifiers

Local EPrints ID: 54730
URI: http://eprints.soton.ac.uk/id/eprint/54730
ISSN: 1018-8827
PURE UUID: 678df6f7-d9df-4c28-a859-f2f0996e4651

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Date deposited: 29 Jul 2008
Last modified: 13 Mar 2019 20:38

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Contributors

Author: Tobias Banaschewski
Author: David Coghill
Author: Paramala Santosh
Author: Alessandro Zuddas
Author: Philip Asherson
Author: Jan Buitelaar
Author: Marina Danckaerts
Author: Manfred Döpfner
Author: Stephen. V. Faraone
Author: Aribert Rothenberger
Author: Joseph Sergeant
Author: Hans-Christoph Steinhausen
Author: Edmund.J.S. Sonuga-Barke
Author: Eric Taylor

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