The University of Southampton
University of Southampton Institutional Repository

P-1B-ATPases - an ancient family of transition metal pumps with diverse functions in plants

P-1B-ATPases - an ancient family of transition metal pumps with diverse functions in plants
P-1B-ATPases - an ancient family of transition metal pumps with diverse functions in plants
P1B-ATPases form a distinct evolutionary sub-family of P-type ATPases, transporting transition metals such as Cu, Zn, Cd, Pb and Co across membranes in a wide range of organisms, including plants. Structurally they are distinct from other P-types, possessing eight transmembrane helices, a CPx/SPC motif in transmembrane domain six, and putative transition metal-binding domains at the N- and/or C-termini. Arabidopsis has eight P1B-ATPases (AtHMA1–AtHMA8), which differ in their structure, function and regulation. They perform a variety of important physiological tasks relating to transition metal transport and homeostasis. The crucial roles of plant P1B-ATPases in micronutrient nutrition, delivery of essential metals to target proteins, and toxic metal detoxification are discussed.
1360-1385
491-502
Williams, Lorraine E.
79ee1856-3732-492b-8ac5-239749c85d9e
Mills, Rebecca F.
dec4afc8-be3b-4517-9038-c3c3e8b71b35
Williams, Lorraine E.
79ee1856-3732-492b-8ac5-239749c85d9e
Mills, Rebecca F.
dec4afc8-be3b-4517-9038-c3c3e8b71b35

Williams, Lorraine E. and Mills, Rebecca F. (2005) P-1B-ATPases - an ancient family of transition metal pumps with diverse functions in plants. Trends in Plant Science, 10 (10), 491-502. (doi:10.1016/j.tplants.2005.08.008).

Record type: Article

Abstract

P1B-ATPases form a distinct evolutionary sub-family of P-type ATPases, transporting transition metals such as Cu, Zn, Cd, Pb and Co across membranes in a wide range of organisms, including plants. Structurally they are distinct from other P-types, possessing eight transmembrane helices, a CPx/SPC motif in transmembrane domain six, and putative transition metal-binding domains at the N- and/or C-termini. Arabidopsis has eight P1B-ATPases (AtHMA1–AtHMA8), which differ in their structure, function and regulation. They perform a variety of important physiological tasks relating to transition metal transport and homeostasis. The crucial roles of plant P1B-ATPases in micronutrient nutrition, delivery of essential metals to target proteins, and toxic metal detoxification are discussed.

Full text not available from this repository.

More information

Published date: October 2005

Identifiers

Local EPrints ID: 55970
URI: https://eprints.soton.ac.uk/id/eprint/55970
ISSN: 1360-1385
PURE UUID: 781bca34-8455-42ba-ac37-a773c174799c

Catalogue record

Date deposited: 08 Aug 2008
Last modified: 17 Jul 2017 14:31

Export record

Altmetrics

Contributors

Author: Rebecca F. Mills

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of https://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×