Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability
Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability
Abbreviations used: 3-MA, 3-methyladenine; 4E-BP1, eIF4E-binding protein 1; BCAA, branched-chain amino acids; CHO, Chinese-hamster ovary; CHX, cycloheximide; D-PBS, Dulbecco's PBS; eIF, eukaryotic initiation factor; GCN2, general control of amino acid biosynthesis, non-derepressing, 2; GSK3, glycogen synthase kinase 3; GST, glutathione S-transferase; hsp, heat-shock protein; JNK, c-Jun N-terminal kinase; MAP kinase, mitogen-activated protein kinase; MAPKAPK-2, MAP kinase-activated kinase-2; mTOR, mammalian target of rapamycin; PKB, protein kinase B; rp, ribosomal protein; S6K, rp S6 kinase; TOP, tract of pyrimidines.
cycloheximide, initiation factor, mRNA translation, phosphorylation, S6 kinase
555-566
Beugnet, A.
27018312-ccab-4990-8ae2-f71a85559fec
Tee, A.R.
1b63bc1f-d26b-447f-9429-e83d2468e068
Taylor, P.M.
329d2e7a-e045-4ee6-9a73-6c423b5c0420
Proud, C.G.
c2cc50f9-4565-4d59-9dfc-aa70b9268a6e
1 June 2003
Beugnet, A.
27018312-ccab-4990-8ae2-f71a85559fec
Tee, A.R.
1b63bc1f-d26b-447f-9429-e83d2468e068
Taylor, P.M.
329d2e7a-e045-4ee6-9a73-6c423b5c0420
Proud, C.G.
c2cc50f9-4565-4d59-9dfc-aa70b9268a6e
Beugnet, A., Tee, A.R., Taylor, P.M. and Proud, C.G.
(2003)
Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability.
Biochemical Journal, 372 (2), .
Abstract
Abbreviations used: 3-MA, 3-methyladenine; 4E-BP1, eIF4E-binding protein 1; BCAA, branched-chain amino acids; CHO, Chinese-hamster ovary; CHX, cycloheximide; D-PBS, Dulbecco's PBS; eIF, eukaryotic initiation factor; GCN2, general control of amino acid biosynthesis, non-derepressing, 2; GSK3, glycogen synthase kinase 3; GST, glutathione S-transferase; hsp, heat-shock protein; JNK, c-Jun N-terminal kinase; MAP kinase, mitogen-activated protein kinase; MAPKAPK-2, MAP kinase-activated kinase-2; mTOR, mammalian target of rapamycin; PKB, protein kinase B; rp, ribosomal protein; S6K, rp S6 kinase; TOP, tract of pyrimidines.
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Submitted date: 12 August 2002
Published date: 1 June 2003
Keywords:
cycloheximide, initiation factor, mRNA translation, phosphorylation, S6 kinase
Identifiers
Local EPrints ID: 56117
URI: http://eprints.soton.ac.uk/id/eprint/56117
ISSN: 1470-8728
PURE UUID: b4927a37-55c3-4d62-afd8-3efb00f14d52
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Date deposited: 06 Aug 2008
Last modified: 08 Jan 2022 19:05
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Contributors
Author:
A. Beugnet
Author:
A.R. Tee
Author:
P.M. Taylor
Author:
C.G. Proud
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