Persistent larval sensory neurons in adult Drosophila melanogaster
Persistent larval sensory neurons in adult Drosophila melanogaster
Using a combination of lineage tracing and laser ablation, we have identified a segmentally repeated array of embryonically produced sensory neurons that persist through metamorphosis into adult stages of Drosophila development. The persistent sensory neurons are found in all unfused abdominal segments, but there is segment-specific variation in the number of neurons observed. There are 12 persistent neurons in the first abdominal segment (A1), 18 in the second (A2), and 16 in segments A3-A7. Most are internal sensory neurons (dendritic arborization neurons and bipolar dendrite neurons), but two are associated with external sensilla on the sternite. All of these neurons and their axons define specific adult sensory pathways in the periphery and their locations and persistence through metamorphosis suggest a role in guiding the growth of adult sensory and motor axons.
development, axon guidance, laser ablation, insect, metamorphosis
275-286
Williams, Darren W.
604e70da-4237-4069-87b0-6dff0917ca49
Shepherd, David
11aa6858-d19c-4450-82ff-11dff9dcd9c4
May 1999
Williams, Darren W.
604e70da-4237-4069-87b0-6dff0917ca49
Shepherd, David
11aa6858-d19c-4450-82ff-11dff9dcd9c4
Abstract
Using a combination of lineage tracing and laser ablation, we have identified a segmentally repeated array of embryonically produced sensory neurons that persist through metamorphosis into adult stages of Drosophila development. The persistent sensory neurons are found in all unfused abdominal segments, but there is segment-specific variation in the number of neurons observed. There are 12 persistent neurons in the first abdominal segment (A1), 18 in the second (A2), and 16 in segments A3-A7. Most are internal sensory neurons (dendritic arborization neurons and bipolar dendrite neurons), but two are associated with external sensilla on the sternite. All of these neurons and their axons define specific adult sensory pathways in the periphery and their locations and persistence through metamorphosis suggest a role in guiding the growth of adult sensory and motor axons.
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Published date: May 1999
Keywords:
development, axon guidance, laser ablation, insect, metamorphosis
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Local EPrints ID: 56188
URI: http://eprints.soton.ac.uk/id/eprint/56188
ISSN: 0022-3034
PURE UUID: e411b113-37b2-4772-bd3a-b1a7f95b4a62
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Date deposited: 22 Aug 2008
Last modified: 06 Aug 2024 01:52
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Author:
Darren W. Williams
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