The University of Southampton
×
Filter your search:
University of Southampton Institutional Repository

The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology

The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology
The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology
The TB Structural Genomics Consortium is an organization devoted to encouraging, coordinating, and facilitating the determination and analysis of structures of proteins from Mycobacterium tuberculosis. The Consortium members hope to work together with other M. tuberculosis researchers to identify M. tuberculosis proteins for which structural information could provide important biological information, to analyze and interpret structures of M. tuberculosis proteins, and to work collaboratively to test ideas about M. tuberculosis protein function that are suggested by structure or related to structural information. This review describes the TB Structural Genomics Consortium and some of the proteins for which the Consortium is in the progress of determining three-dimensional structures.
protein structure, X-ray crystallography, structural genomics, mycobacterium tuberculosis, drug discovery
1472-9792
223-249
Terwilliger, T.C.
063d6393-8a19-4c79-b499-8066e3f44639
Park, M.S.
45736d6a-d607-427e-8565-f5489f1e80eb
Waldo, G.S.
01809500-eff2-4796-8a5b-4402ed5c2273
Berendzen, J.
f4a0539d-7558-4ef3-bbad-f9f572621a4e
Hung, L.W.
182a1845-cf67-4e18-bc62-cfa5ca5f364a
Kim, C.Y.
bf65b85d-8cf2-4728-b045-06ad8163102d
Smith, C.V.
9f158f6d-deac-42e4-bcda-3772ad8591d7
Sacchettini, J.C.
31599e47-7794-44f0-a305-bc30a4d8ac75
Bellinzoni, M.
984987e0-4c17-40a4-9c18-31bb8c7bcdf5
Bossi, R.
1301b0a9-3ed9-46a9-bd1e-2deba1ea10bd
Rossi, E.
33698bc6-5ba7-4327-a08d-384bf19d702d
Mattevi, A.
ad946c35-c5ad-411f-a30e-35822e748230
Milano, A.
a6278dce-7278-4558-a8ef-16a72eb90ded
Riccardi, G.
c374d140-049c-4cda-a9f7-fc2e12fb7788
Rizzi, M.
4c2e4b03-87ef-407b-8647-b63d3cb15388
Roberts, M.M.
12a654b2-533e-4cbc-a579-9719993cfaee
Coker, A.R.
0a992f86-46af-48c9-be7b-7d3e215cc158
Fossati, G.
c53382ce-0504-4e7e-9a04-1fbc8a3f5677
Mascagni, P.
3afbb212-88ce-414f-a148-5bba6e63fbbf
Coates, A.R.M.
c60f45be-2ea0-4157-9362-c51275591bf6
Wood, S.P.
430faabf-7f5c-4cf6-9bcc-5955f5e09566
Goulding, C.W.
90fb52d0-3411-4e31-a696-2e56b9ac9717
Apostol, M.I.
f99b47dc-9761-4734-b205-771d8becbf02
Anderson, D.H.
1575e222-781d-4ed8-899b-143d31a6177b
Gill, H.S.
628a5421-2d90-4b3b-8aea-99f7fd135718
Eisenberg, D.S.
e590978f-cd98-416a-8285-7be9f50fa250
Taneja, B.
ab385ea6-a6f2-4c3b-aa37-f584156f85a1
Mande, S.
7f32b81e-ee23-4b5e-8bee-2c334e689661
Pohl, E.
13119fdf-4b69-4605-b75c-274127b90bc8
Lamzin, V.
4b69101b-115d-4c2a-98a4-0207076b45f9
Tucker, P.
d6f30b15-2c5c-42cd-94f5-62e58a9ada9d
Wilmanns, M.
83b55fae-6ebb-4499-b32d-795f2ddbcbf3
Colovos, C.
e02043c5-b2f3-4f78-ab02-4bef0a1ab3ce
Meyer-Klaucke, W.
b11f021b-bdd0-4710-89cd-73c7f2e8db21
Munro, A.W.
80945271-0dae-4b93-b078-604c3699121f
McLean, K.J.
646f75e1-d6a3-43b4-b216-c5e445dd37b3
Marshall, K.R.
96251a18-f0d5-403e-8fde-5cb5c1a31178
Leys, D.
cc7d401b-20ae-4fe1-bc62-320e2a22b084
Yang, J.K.
224035c7-56bb-43ff-925f-c5567a6dccd7
Yoon, H.J.
e8088079-2600-4673-86ff-2f8042d8a1f9
Lee, B.I.
0fdd01d0-f691-46f5-996d-fd519866f51c
Lee, M.G.
2d1c4304-053b-4d37-8eb2-55681b9619f7
Kwak, J.E.
dd383b48-34ae-40fb-bb13-8e5d4f1a73ca
Han, B.W.
d4846854-1067-4c26-a3d6-36f4d202a18c
Lee, J.Y.
06f3dfa6-5194-4015-a2b5-58e9376553dd
Baek, S.H.
c7da5387-b875-471e-9f43-be5699644993
Suh, S.W.
2e5f7b97-1908-481e-9bde-11ee6574b5df
Komen, M.M.
56551e36-b1f4-4aed-83d6-317f9de55c81
Arcus, V.L.
ebcbda67-92f0-469a-8584-96def8670505
Baker, E.N.
135a4144-bb03-422e-abeb-4a668ade5b3b
Lott, J.S.
6aaab215-fcd2-4d46-a7aa-e6677837e85b
Jacobs, W.
969f917a-4b03-494b-8a4a-d9d7511bf195
Alber, T.
0ba0f01d-c58e-4b4c-8b25-b75879081aec
Rupp, B.
b2e7b852-7c96-4e1f-838a-d27fdd3ce95d
Terwilliger, T.C.
063d6393-8a19-4c79-b499-8066e3f44639
Park, M.S.
45736d6a-d607-427e-8565-f5489f1e80eb
Waldo, G.S.
01809500-eff2-4796-8a5b-4402ed5c2273
Berendzen, J.
f4a0539d-7558-4ef3-bbad-f9f572621a4e
Hung, L.W.
182a1845-cf67-4e18-bc62-cfa5ca5f364a
Kim, C.Y.
bf65b85d-8cf2-4728-b045-06ad8163102d
Smith, C.V.
9f158f6d-deac-42e4-bcda-3772ad8591d7
Sacchettini, J.C.
31599e47-7794-44f0-a305-bc30a4d8ac75
Bellinzoni, M.
984987e0-4c17-40a4-9c18-31bb8c7bcdf5
Bossi, R.
1301b0a9-3ed9-46a9-bd1e-2deba1ea10bd
Rossi, E.
33698bc6-5ba7-4327-a08d-384bf19d702d
Mattevi, A.
ad946c35-c5ad-411f-a30e-35822e748230
Milano, A.
a6278dce-7278-4558-a8ef-16a72eb90ded
Riccardi, G.
c374d140-049c-4cda-a9f7-fc2e12fb7788
Rizzi, M.
4c2e4b03-87ef-407b-8647-b63d3cb15388
Roberts, M.M.
12a654b2-533e-4cbc-a579-9719993cfaee
Coker, A.R.
0a992f86-46af-48c9-be7b-7d3e215cc158
Fossati, G.
c53382ce-0504-4e7e-9a04-1fbc8a3f5677
Mascagni, P.
3afbb212-88ce-414f-a148-5bba6e63fbbf
Coates, A.R.M.
c60f45be-2ea0-4157-9362-c51275591bf6
Wood, S.P.
430faabf-7f5c-4cf6-9bcc-5955f5e09566
Goulding, C.W.
90fb52d0-3411-4e31-a696-2e56b9ac9717
Apostol, M.I.
f99b47dc-9761-4734-b205-771d8becbf02
Anderson, D.H.
1575e222-781d-4ed8-899b-143d31a6177b
Gill, H.S.
628a5421-2d90-4b3b-8aea-99f7fd135718
Eisenberg, D.S.
e590978f-cd98-416a-8285-7be9f50fa250
Taneja, B.
ab385ea6-a6f2-4c3b-aa37-f584156f85a1
Mande, S.
7f32b81e-ee23-4b5e-8bee-2c334e689661
Pohl, E.
13119fdf-4b69-4605-b75c-274127b90bc8
Lamzin, V.
4b69101b-115d-4c2a-98a4-0207076b45f9
Tucker, P.
d6f30b15-2c5c-42cd-94f5-62e58a9ada9d
Wilmanns, M.
83b55fae-6ebb-4499-b32d-795f2ddbcbf3
Colovos, C.
e02043c5-b2f3-4f78-ab02-4bef0a1ab3ce
Meyer-Klaucke, W.
b11f021b-bdd0-4710-89cd-73c7f2e8db21
Munro, A.W.
80945271-0dae-4b93-b078-604c3699121f
McLean, K.J.
646f75e1-d6a3-43b4-b216-c5e445dd37b3
Marshall, K.R.
96251a18-f0d5-403e-8fde-5cb5c1a31178
Leys, D.
cc7d401b-20ae-4fe1-bc62-320e2a22b084
Yang, J.K.
224035c7-56bb-43ff-925f-c5567a6dccd7
Yoon, H.J.
e8088079-2600-4673-86ff-2f8042d8a1f9
Lee, B.I.
0fdd01d0-f691-46f5-996d-fd519866f51c
Lee, M.G.
2d1c4304-053b-4d37-8eb2-55681b9619f7
Kwak, J.E.
dd383b48-34ae-40fb-bb13-8e5d4f1a73ca
Han, B.W.
d4846854-1067-4c26-a3d6-36f4d202a18c
Lee, J.Y.
06f3dfa6-5194-4015-a2b5-58e9376553dd
Baek, S.H.
c7da5387-b875-471e-9f43-be5699644993
Suh, S.W.
2e5f7b97-1908-481e-9bde-11ee6574b5df
Komen, M.M.
56551e36-b1f4-4aed-83d6-317f9de55c81
Arcus, V.L.
ebcbda67-92f0-469a-8584-96def8670505
Baker, E.N.
135a4144-bb03-422e-abeb-4a668ade5b3b
Lott, J.S.
6aaab215-fcd2-4d46-a7aa-e6677837e85b
Jacobs, W.
969f917a-4b03-494b-8a4a-d9d7511bf195
Alber, T.
0ba0f01d-c58e-4b4c-8b25-b75879081aec
Rupp, B.
b2e7b852-7c96-4e1f-838a-d27fdd3ce95d

Terwilliger, T.C., Park, M.S., Waldo, G.S., Berendzen, J., Hung, L.W., Kim, C.Y., Smith, C.V., Sacchettini, J.C., Bellinzoni, M., Bossi, R., Rossi, E., Mattevi, A., Milano, A., Riccardi, G., Rizzi, M., Roberts, M.M., Coker, A.R., Fossati, G., Mascagni, P., Coates, A.R.M., Wood, S.P., Goulding, C.W., Apostol, M.I., Anderson, D.H., Gill, H.S., Eisenberg, D.S., Taneja, B., Mande, S., Pohl, E., Lamzin, V., Tucker, P., Wilmanns, M., Colovos, C., Meyer-Klaucke, W., Munro, A.W., McLean, K.J., Marshall, K.R., Leys, D., Yang, J.K., Yoon, H.J., Lee, B.I., Lee, M.G., Kwak, J.E., Han, B.W., Lee, J.Y., Baek, S.H., Suh, S.W., Komen, M.M., Arcus, V.L., Baker, E.N., Lott, J.S., Jacobs, W., Alber, T. and Rupp, B. (2003) The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology. Tuberculosis, 83 (4), 223-249. (doi:10.1016/S1472-9792(03)00051-9).

Record type: Article

Abstract

The TB Structural Genomics Consortium is an organization devoted to encouraging, coordinating, and facilitating the determination and analysis of structures of proteins from Mycobacterium tuberculosis. The Consortium members hope to work together with other M. tuberculosis researchers to identify M. tuberculosis proteins for which structural information could provide important biological information, to analyze and interpret structures of M. tuberculosis proteins, and to work collaboratively to test ideas about M. tuberculosis protein function that are suggested by structure or related to structural information. This review describes the TB Structural Genomics Consortium and some of the proteins for which the Consortium is in the progress of determining three-dimensional structures.

This record has no associated files available for download.

More information

Published date: 1 January 2003
Keywords: protein structure, X-ray crystallography, structural genomics, mycobacterium tuberculosis, drug discovery
Learn more about Biological Sciences research

Identifiers

Local EPrints ID: 56633
URI: http://eprints.soton.ac.uk/id/eprint/56633
DOI: doi:10.1016/S1472-9792(03)00051-9
ISSN: 1472-9792
PURE UUID: 09efe450-d94b-4b32-9442-b97e2c4b9941

Catalogue record

Date deposited: 11 Aug 2008
Last modified: 15 Mar 2024 11:02

Export record

Altmetrics

Contributors

Author: T.C. Terwilliger
Author: M.S. Park
Author: G.S. Waldo
Author: J. Berendzen
Author: L.W. Hung
Author: C.Y. Kim
Author: C.V. Smith
Author: J.C. Sacchettini
Author: M. Bellinzoni
Author: R. Bossi
Author: E. Rossi
Author: A. Mattevi
Author: A. Milano
Author: G. Riccardi
Author: M. Rizzi
Author: M.M. Roberts
Author: A.R. Coker
Author: G. Fossati
Author: P. Mascagni
Author: A.R.M. Coates
Author: S.P. Wood
Author: C.W. Goulding
Author: M.I. Apostol
Author: D.H. Anderson
Author: H.S. Gill
Author: D.S. Eisenberg
Author: B. Taneja
Author: S. Mande
Author: E. Pohl
Author: V. Lamzin
Author: P. Tucker
Author: M. Wilmanns
Author: C. Colovos
Author: W. Meyer-Klaucke
Author: A.W. Munro
Author: K.J. McLean
Author: K.R. Marshall
Author: D. Leys
Author: J.K. Yang
Author: H.J. Yoon
Author: B.I. Lee
Author: M.G. Lee
Author: J.E. Kwak
Author: B.W. Han
Author: J.Y. Lee
Author: S.H. Baek
Author: S.W. Suh
Author: M.M. Komen
Author: V.L. Arcus
Author: E.N. Baker
Author: J.S. Lott
Author: W. Jacobs
Author: T. Alber
Author: B. Rupp

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Library staff additional information
Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×