Yin, H.B., Brown, T., Wilkinson, J.S., Eason, R.W. and Melvin, T.
Photonic generation of DNA micropatterns for haplotype analysis
At BioScience 2005.
01 Jul 2005.
Full text not available from this repository.
Genotype analysis of single nucleotide polymorphism is a straight-forward process with many system becoming available including mass spectrometry, microbeads and solid phase microarry approaches; methodologies for easy analysis of long stretches of DNA (10000s of base pair ling) are now needed for haplotype identification. To meet this need, we are developing a novel biosensor in silicon, which are suitable for miniaturization and integrated DNA analysis.
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