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The development of a passive acoustic device for monitoring the effectiveness of shockwave lithotripsy in real time

The development of a passive acoustic device for monitoring the effectiveness of shockwave lithotripsy in real time
The development of a passive acoustic device for monitoring the effectiveness of shockwave lithotripsy in real time
This paper reports how laboratory experiments and hydrocode simulations (of cavitation and shock wave propagation) have been used to generate a clinical device which can deliver real benefit to patients with kidney stones. Currently X-ray or ultrasound B-scan imaging are used to locate the stone and to check that it remains targeted at the focus of the lithotripter during treatment. Neither imaging method is particularly effective in allowing the efficacy of treatment to be judged during the treatment session. In this study, laboratory experiment and Computational Fluid Dynamics simulations of the complex interactions between the shock wave, the stone, and the human tissue, have been used to develop a new clinical device. This device, which has been tested in clinical trials, exploits the passive acoustic emissions generated by these interactions, to identify whether the stone remains in the focus, and to what extent the treatment has been successful.
159-180
Leighton, Timothy
3e5262ce-1d7d-42eb-b013-fcc5c286bbae
Fedele, Fiammetta
dacbf64a-ef35-49e3-9300-8c4c1bf0b565
Coleman, Andrew
c9c24057-9e1f-4b62-b916-6a7c64daa78b
McCarthy, Catherine
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Jamaluddin, Ahmad
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Turangan, Cary
7fa74af1-de1a-40ca-81f3-2620b6daa649
Ball, Graham
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Ryves, Simon
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Hurrell, Andrew
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De Stefano, Antonello
fb7b0944-88ab-4dae-9a53-504f2723960c
White, Paul
2dd2477b-5aa9-42e2-9d19-0806d994eaba
Leighton, Timothy
3e5262ce-1d7d-42eb-b013-fcc5c286bbae
Fedele, Fiammetta
dacbf64a-ef35-49e3-9300-8c4c1bf0b565
Coleman, Andrew
c9c24057-9e1f-4b62-b916-6a7c64daa78b
McCarthy, Catherine
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Jamaluddin, Ahmad
3c16e47c-c293-457a-afab-70147fdea612
Turangan, Cary
7fa74af1-de1a-40ca-81f3-2620b6daa649
Ball, Graham
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Ryves, Simon
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Hurrell, Andrew
c98f0f5c-eb7c-46e6-90c4-98c220148a24
De Stefano, Antonello
fb7b0944-88ab-4dae-9a53-504f2723960c
White, Paul
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Leighton, Timothy, Fedele, Fiammetta, Coleman, Andrew, McCarthy, Catherine, Jamaluddin, Ahmad, Turangan, Cary, Ball, Graham, Ryves, Simon, Hurrell, Andrew, De Stefano, Antonello and White, Paul (2008) The development of a passive acoustic device for monitoring the effectiveness of shockwave lithotripsy in real time. Hydroacoustics, 11, 159-180.

Record type: Article

Abstract

This paper reports how laboratory experiments and hydrocode simulations (of cavitation and shock wave propagation) have been used to generate a clinical device which can deliver real benefit to patients with kidney stones. Currently X-ray or ultrasound B-scan imaging are used to locate the stone and to check that it remains targeted at the focus of the lithotripter during treatment. Neither imaging method is particularly effective in allowing the efficacy of treatment to be judged during the treatment session. In this study, laboratory experiment and Computational Fluid Dynamics simulations of the complex interactions between the shock wave, the stone, and the human tissue, have been used to develop a new clinical device. This device, which has been tested in clinical trials, exploits the passive acoustic emissions generated by these interactions, to identify whether the stone remains in the focus, and to what extent the treatment has been successful.

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More information

Published date: 2008

Identifiers

Local EPrints ID: 57860
URI: http://eprints.soton.ac.uk/id/eprint/57860
PURE UUID: d0f3e803-4045-4138-81d5-6d4654e42745
ORCID for Timothy Leighton: ORCID iD orcid.org/0000-0002-1649-8750
ORCID for Paul White: ORCID iD orcid.org/0000-0002-4787-8713

Catalogue record

Date deposited: 21 Aug 2008
Last modified: 11 Jul 2024 01:34

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Contributors

Author: Fiammetta Fedele
Author: Andrew Coleman
Author: Catherine McCarthy
Author: Ahmad Jamaluddin
Author: Cary Turangan
Author: Graham Ball
Author: Simon Ryves
Author: Andrew Hurrell
Author: Antonello De Stefano
Author: Paul White ORCID iD

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