Hitchhikers' guide to the leukemia genome
Hitchhikers' guide to the leukemia genome
TKs have been implicated in the pathogenesis of diverse malignancies and often serve as excellent drug targets. Partial mutation scanning of the tyrosine kinome in AML has revealed a paucity of new causative abnormalities in a larger background of previously unknown single-nucleotide polymorphisms and somatically acquired passenger mutations that hitchhike a ride with the malignant clone.
genome, leukemia
4428-4429
Cross, Nicholas C.
f87650da-b908-4a34-b31b-d62c5f186fe4
1 May 2008
Cross, Nicholas C.
f87650da-b908-4a34-b31b-d62c5f186fe4
Cross, Nicholas C.
(2008)
Hitchhikers' guide to the leukemia genome.
Blood, 111 (9), .
Abstract
TKs have been implicated in the pathogenesis of diverse malignancies and often serve as excellent drug targets. Partial mutation scanning of the tyrosine kinome in AML has revealed a paucity of new causative abnormalities in a larger background of previously unknown single-nucleotide polymorphisms and somatically acquired passenger mutations that hitchhike a ride with the malignant clone.
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Published date: 1 May 2008
Keywords:
genome, leukemia
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Local EPrints ID: 59627
URI: http://eprints.soton.ac.uk/id/eprint/59627
ISSN: 0006-4971
PURE UUID: e585c6cb-cdc7-46c5-adda-94448e5d532e
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Date deposited: 02 Sep 2008
Last modified: 23 Jul 2022 01:49
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