Metabolism and developmental competence of the preimplantation embryo
Metabolism and developmental competence of the preimplantation embryo
In vitro fertilisation (IVF) has permitted many thousands of couples to conceive world-wide yet is limited by low success rates and a confounding high multiple birth rate due to the transfer of more than one embryo. These problems could be overcome if single embryos of known developmental competence could be selected for replacement. It is clear that current embryo selection methods, which rely on morphological appearance alone, are poor predictors of viability. Metabolism is intrinsic to embryo health and much research has concentrated on developing a non-invasive metabolic marker of developmental competence
preimplantation embryo metabolism, oxygen consumption, ATP, reactive oxygen species, amino acid turnover
S92-S96
Houghton, Franchesca D.
53946041-127e-45a8-9edb-bf4b3c23005f
Leese, Henry J.
0aee3eba-6732-4568-8f3f-93b3222c0b88
July 2004
Houghton, Franchesca D.
53946041-127e-45a8-9edb-bf4b3c23005f
Leese, Henry J.
0aee3eba-6732-4568-8f3f-93b3222c0b88
Houghton, Franchesca D. and Leese, Henry J.
(2004)
Metabolism and developmental competence of the preimplantation embryo.
European Journal of Obstetrics, Gynecology and Reproductive Biology, 115 (Supplement 1), .
(doi:10.1016/j.ejogrb.2004.01.019).
Abstract
In vitro fertilisation (IVF) has permitted many thousands of couples to conceive world-wide yet is limited by low success rates and a confounding high multiple birth rate due to the transfer of more than one embryo. These problems could be overcome if single embryos of known developmental competence could be selected for replacement. It is clear that current embryo selection methods, which rely on morphological appearance alone, are poor predictors of viability. Metabolism is intrinsic to embryo health and much research has concentrated on developing a non-invasive metabolic marker of developmental competence
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Published date: July 2004
Keywords:
preimplantation embryo metabolism, oxygen consumption, ATP, reactive oxygen species, amino acid turnover
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Local EPrints ID: 59852
URI: http://eprints.soton.ac.uk/id/eprint/59852
ISSN: 0301-2115
PURE UUID: 0266d3ae-3d3e-4e28-a71f-b8de1bbe27b4
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Date deposited: 24 Nov 2008
Last modified: 16 Mar 2024 03:49
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Author:
Henry J. Leese
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