Human embryo and early fetus research
Human embryo and early fetus research
Studies of human embryos and fetuses have highlighted developmental differences between humans and model organisms. In addition to describing the normal biology of our own species, a justification in itself, studies of early human development have aided identification of candidate disease genes mapped by positional cloning strategies, understanding pathophysiology, where human disorders are not faithfully reproduced by models in other species, and, more recently, potential therapies based on human embryonic stem and embryonic germ cells. In this article, we review these applications. We also discuss when and how to study human embryo and early fetuses and some of the regulations of this research
research, fetus, human, embryo research, gene expression profiling, ethics, genetics, sex determination (genetics), embryo, models, disease, legislation & jurisprudence, research support, vertebrates, germ cells, genes, biology, animal, stem cells, therapy, review, humans, animals, gene expression regulation, fetal research, developmental, embryology
98-107
Ostrer, H.
564ec942-c5f0-4b25-b08b-b1a23a8d3f5e
Wilson, D.I.
1500fca1-7082-4271-95f4-691f1d1252a2
Hanley, N.A.
ac5bcdcc-51dd-4f2c-ad06-fef6c1d50ebd
August 2006
Ostrer, H.
564ec942-c5f0-4b25-b08b-b1a23a8d3f5e
Wilson, D.I.
1500fca1-7082-4271-95f4-691f1d1252a2
Hanley, N.A.
ac5bcdcc-51dd-4f2c-ad06-fef6c1d50ebd
Abstract
Studies of human embryos and fetuses have highlighted developmental differences between humans and model organisms. In addition to describing the normal biology of our own species, a justification in itself, studies of early human development have aided identification of candidate disease genes mapped by positional cloning strategies, understanding pathophysiology, where human disorders are not faithfully reproduced by models in other species, and, more recently, potential therapies based on human embryonic stem and embryonic germ cells. In this article, we review these applications. We also discuss when and how to study human embryo and early fetuses and some of the regulations of this research
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Published date: August 2006
Keywords:
research, fetus, human, embryo research, gene expression profiling, ethics, genetics, sex determination (genetics), embryo, models, disease, legislation & jurisprudence, research support, vertebrates, germ cells, genes, biology, animal, stem cells, therapy, review, humans, animals, gene expression regulation, fetal research, developmental, embryology
Identifiers
Local EPrints ID: 60108
URI: http://eprints.soton.ac.uk/id/eprint/60108
ISSN: 0009-9163
PURE UUID: bc779934-a87a-45bd-a598-d7d6320d2f5c
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Date deposited: 05 Sep 2008
Last modified: 15 Mar 2024 11:19
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Author:
H. Ostrer
Author:
N.A. Hanley
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