The delivery of PEBBLE nanosensors to measure the intracellular environment
The delivery of PEBBLE nanosensors to measure the intracellular environment
Cellular introduction of PEBBLEs (photonic explorers for bioanalysis with biologically localized embedding) has been investigated by a wide variety of methods in a range of cell types. These methods include surface functionalization with CPPs (cell-penetrating peptides), pinocytosis, commercial lipid transfection agents, cytochalasin D, picoinjection, and Gene gun bombardment. This paper will overview several of the most popular methods used for the introduction of PEBBLE nanosensors to the cellular environment and discuss the efficacy of the techniques.
biolistics, delivery, transfection, mice, review, intracellular fluid, research, rats, nanotechnology, biosensing techniques, animals, phagocytosis, microscopy, humans, paper, cytochalasin d, methods, environment, peptides, confocal, agents, research support, pinocytosis, microinjections, chemistry
538-543
Webster, A.
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Houghton, F.D.
53946041-127e-45a8-9edb-bf4b3c23005f
Leese, H.J.
1f369c23-4361-4534-a093-54699ec5eceb
Aylott, J.W.
4ceda9c2-eb95-430c-8ff5-77c37f8668dc
2007
Webster, A.
33fffdd7-2867-4e34-9f8f-ae4f54856341
Houghton, F.D.
53946041-127e-45a8-9edb-bf4b3c23005f
Leese, H.J.
1f369c23-4361-4534-a093-54699ec5eceb
Aylott, J.W.
4ceda9c2-eb95-430c-8ff5-77c37f8668dc
Webster, A., Houghton, F.D., Leese, H.J. and Aylott, J.W.
(2007)
The delivery of PEBBLE nanosensors to measure the intracellular environment.
Biochemical Society Transactions, 35 (3), .
Abstract
Cellular introduction of PEBBLEs (photonic explorers for bioanalysis with biologically localized embedding) has been investigated by a wide variety of methods in a range of cell types. These methods include surface functionalization with CPPs (cell-penetrating peptides), pinocytosis, commercial lipid transfection agents, cytochalasin D, picoinjection, and Gene gun bombardment. This paper will overview several of the most popular methods used for the introduction of PEBBLE nanosensors to the cellular environment and discuss the efficacy of the techniques.
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Published date: 2007
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Biochemical Society Focused Meetings
Keywords:
biolistics, delivery, transfection, mice, review, intracellular fluid, research, rats, nanotechnology, biosensing techniques, animals, phagocytosis, microscopy, humans, paper, cytochalasin d, methods, environment, peptides, confocal, agents, research support, pinocytosis, microinjections, chemistry
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Local EPrints ID: 60404
URI: http://eprints.soton.ac.uk/id/eprint/60404
ISSN: 0300-5127
PURE UUID: ee1fce0b-d4f2-43bb-b1bd-f8f973b8b147
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Date deposited: 02 Sep 2008
Last modified: 27 Apr 2022 01:49
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Author:
A. Webster
Author:
H.J. Leese
Author:
J.W. Aylott
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