The University of Southampton
University of Southampton Institutional Repository

Persistence with teriparatide in patients with osteoporosis: the UK experience

Arden, N.K., Earl, S., Fisher, D.J., Cooper, C., Carruthers, S. and Goater, M. (2006) Persistence with teriparatide in patients with osteoporosis: the UK experience Osteoporosis International, 17, (11), pp. 1626-1629. (doi:10.1007/s00198-006-0171-5).

Record type: Article


INTRODUCTION: The objective of this paper was to determine the persistence with teriparatide at 12 months in all patients in the UK who were prescribed the treatment since its launch.
METHODS: Virtually all patients prescribed teriparatide in the UK receive treatment through Healthcare at Home, Basingstoke, UK. Data was obtained to assess the start date, discontinuation date and reason for discontinuation in all patients receiving teriparatide since its launch. Persistence was defined as the number of patients continuing treatment.
RESULTS: A total of 1,104 patients were included in the analysis. The median duration of use in all patients was 252 days. Of the 435 patients who were at least 12 months post-initiation of treatment, persistence was 87%. Forty-two patients (3.8%) had discontinued treatment due to adverse events.
CONCLUSIONS: This study demonstrates that persistence with teriparatide at 12 months is very high and is probably greater than that of existing oral therapies for osteoporosis. The reasons for the high persistence rates seen with teriparatide are likely to be multi-factorial. The high persistence rates should help to optimise the effectiveness of therapy in this group of high-risk patients.

Full text not available from this repository.

More information

Published date: 2006
Keywords: therapy, analysis, osteoporosis, methods, teriparatide, bone


Local EPrints ID: 60870
ISSN: 0937-941X
PURE UUID: 029879cf-e01f-4049-964e-bc8fcf1d69c3
ORCID for C. Cooper: ORCID iD

Catalogue record

Date deposited: 09 Sep 2008
Last modified: 17 Jul 2017 14:23

Export record



Author: N.K. Arden
Author: S. Earl
Author: D.J. Fisher
Author: C. Cooper ORCID iD
Author: S. Carruthers
Author: M. Goater

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton:

ePrints Soton supports OAI 2.0 with a base URL of

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.