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Non-bacterial thrombotic endocarditis

Non-bacterial thrombotic endocarditis
Non-bacterial thrombotic endocarditis
Non-bacterial thrombotic endocarditis (NBTE) is a disease characterised by the presence of vegetations on cardiac valves, which consist of fibrin and platelet aggregates and devoid of inflammation or bacteria. NBTE has increasingly been recognised as a condition associated with numerous diseases and a potentially life-threatening source of thromboembolism. NBTE is not a common entity; however it is frequently underestimated, probably due to underlying diseases (cancer, autoimmune disorders, HIV). NBTE is difficult to diagnose and relies on strong clinical suspicion. NBTE is also difficult to manage and each case should be individually managed by identifying and treating the underlying pathology. Surgical intervention is not recommended unless the patient is in acute congestive failure.
endocarditis, pathology, etiology, thromboembolism, review, cancer, disease, inflammation, heart valve diseases, humans
1010-7940
696-701
Asopa, Sanjay
d55c26b7-8460-447b-bd39-70d13e1b1419
Patel, Anish
f6084799-26c7-4053-9ec1-24596d413b9c
Khan, Omar A.
e6bbb536-9991-48be-a54d-4fbce6284238
Sharma, Rajan
c920ebfe-8a06-43b1-876f-9cbb9649fa49
Ohri, Sunil K.
8aa5698c-78cf-4f59-a5af-5afa46f0348c
Asopa, Sanjay
d55c26b7-8460-447b-bd39-70d13e1b1419
Patel, Anish
f6084799-26c7-4053-9ec1-24596d413b9c
Khan, Omar A.
e6bbb536-9991-48be-a54d-4fbce6284238
Sharma, Rajan
c920ebfe-8a06-43b1-876f-9cbb9649fa49
Ohri, Sunil K.
8aa5698c-78cf-4f59-a5af-5afa46f0348c

Asopa, Sanjay, Patel, Anish, Khan, Omar A., Sharma, Rajan and Ohri, Sunil K. (2007) Non-bacterial thrombotic endocarditis. European Journal of Cardio-thoracic Surgery, 32 (5), 696-701. (doi:10.1016/j.ejcts.2007.07.029).

Record type: Article

Abstract

Non-bacterial thrombotic endocarditis (NBTE) is a disease characterised by the presence of vegetations on cardiac valves, which consist of fibrin and platelet aggregates and devoid of inflammation or bacteria. NBTE has increasingly been recognised as a condition associated with numerous diseases and a potentially life-threatening source of thromboembolism. NBTE is not a common entity; however it is frequently underestimated, probably due to underlying diseases (cancer, autoimmune disorders, HIV). NBTE is difficult to diagnose and relies on strong clinical suspicion. NBTE is also difficult to manage and each case should be individually managed by identifying and treating the underlying pathology. Surgical intervention is not recommended unless the patient is in acute congestive failure.

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More information

Published date: November 2007
Keywords: endocarditis, pathology, etiology, thromboembolism, review, cancer, disease, inflammation, heart valve diseases, humans

Identifiers

Local EPrints ID: 60877
URI: https://eprints.soton.ac.uk/id/eprint/60877
ISSN: 1010-7940
PURE UUID: 2fce6ea9-5033-4ca6-97ae-4f3b1dafbf7b

Catalogue record

Date deposited: 26 Sep 2008
Last modified: 13 Mar 2019 20:29

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