Batty, G. D., Shipley, M. J., Mortensen, L. H., Gale, C. R. and Deary, I. J.
IQ in late adolescence/early adulthood, risk factors in middle-age and later coronary heart disease mortality in men: the Vietnam Experience Study
European Journal Cardiovascular Prevention & Rehabilitation, 15, (3), .
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OBJECTIVE: Examine the relation between IQ in early adulthood and later coronary heart disease (CHD) mortality, and assess the extent to which established risk factors measured in middle-age might explain this gradient.
DESIGN: Cohort study of 4316 male former Vietnam-era US army personnel with IQ scores (mean age 20.4 years), risk factor data (mean age 38.3 years) and 15 years mortality surveillance.
RESULTS: In age-adjusted analyses, lower IQ scores were associated with an increased rate of CHD mortality (hazard ratio per SD decrease in IQ; 95% confidence interval: 1.34; 1.00, 1.79). Adjustment for later chronic disease (1.22; 0.91, 1.64), behavioural (1.29; 0.95, 1.74) and physiological risk factors (1.19; 0.88, 1.62) led to some attenuation of this gradient. This attenuation was particularly pronounced on adding socioeconomic indices to the multivariable model when the IQ-CHD relation was eliminated (1.05; 0.73, 1.52). A similar pattern of association was apparent when cardiovascular disease was the outcome of interest.
CONCLUSION: High IQ may lead to educational success, well remunerated and higher prestige employment, and this pathway may confer cardio-protection.
||cardiovascular-disease, coronary heart disease, men, risk, cardiovascular, middle age, male, cohort studies, risk factors, cohort, disease, heart, employment, cardiovascular disease, mortality, chronic disease
||24 Sep 2008
||16 Apr 2017 17:32
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