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Long-term outcome following total hip arthroplasty: A controlled longitudinal study

Long-term outcome following total hip arthroplasty: A controlled longitudinal study
Long-term outcome following total hip arthroplasty: A controlled longitudinal study
OBJECTIVE: To assess long-term outcome and predictors of prognosis following total hip arthroplasty (THA) for osteoarthritis (OA). METHODS: We studied 282 patients from 2 English health districts approximately 8 years after THA, along with 295 controls selected from the general population. Baseline data were collected by interview and examination, on sex, age, comorbidity, body mass index (BMI), and Short Form 36 (SF-36) functional status, and preoperative radiographic severity of OA was graded. Functional status was reassessed at followup by postal questionnaire. Predictors of change in physical functioning were analyzed by linear regression. RESULTS: Over followup, cases who had THA reported a median improvement of 10 points in SF-36 score for physical functioning, whereas in controls there was a median deterioration of 10 points (P < 0.0001). Mental health improved by a median of 12 points in both cases and controls. Change in physical functioning was significantly worse in women and at older ages among both cases and controls. In cases, Croft grade 5 OA was associated with a physical functioning score improvement 19.4 points (95% confidence interval 7.7, 31.2) greater than the improvement in grades 0-3, but BMI was unrelated to change in physical functioning. CONCLUSION: Improvements in physical functioning following THA for OA are sustained in the long term and are more frequent in patients with more severe radiographic features preoperatively. We found no indication that patients who are overweight benefit less from THA, but further evidence is needed on the prognostic influence of more severe obesity
women, overweight, osteoarthritis, body mass index, methods, longitudinal studies, health, obesity, bone, prognosis, mental health, hip, comorbidity
0893-7524
1375-1380
Cushnaghan, J.
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Coggon, D.
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Reading, I.
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Croft, P.
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Byng, P.
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Cox, K.
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Dieppe, P.
293f54b1-2f1a-4dd1-ad56-88ab75dab64e
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Cushnaghan, J.
fb4ffb9b-caf7-42f5-8fb2-5ce279d4ef2b
Coggon, D.
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Reading, I.
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Croft, P.
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Byng, P.
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Cox, K.
7305c27e-9cdc-4e37-b994-ac55d7d1dfd2
Dieppe, P.
293f54b1-2f1a-4dd1-ad56-88ab75dab64e
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6

Cushnaghan, J., Coggon, D., Reading, I., Croft, P., Byng, P., Cox, K., Dieppe, P. and Cooper, C. (2007) Long-term outcome following total hip arthroplasty: A controlled longitudinal study. Arthritis Care & Research, 57 (8), 1375-1380. (doi:10.1002/art.23101).

Record type: Article

Abstract

OBJECTIVE: To assess long-term outcome and predictors of prognosis following total hip arthroplasty (THA) for osteoarthritis (OA). METHODS: We studied 282 patients from 2 English health districts approximately 8 years after THA, along with 295 controls selected from the general population. Baseline data were collected by interview and examination, on sex, age, comorbidity, body mass index (BMI), and Short Form 36 (SF-36) functional status, and preoperative radiographic severity of OA was graded. Functional status was reassessed at followup by postal questionnaire. Predictors of change in physical functioning were analyzed by linear regression. RESULTS: Over followup, cases who had THA reported a median improvement of 10 points in SF-36 score for physical functioning, whereas in controls there was a median deterioration of 10 points (P < 0.0001). Mental health improved by a median of 12 points in both cases and controls. Change in physical functioning was significantly worse in women and at older ages among both cases and controls. In cases, Croft grade 5 OA was associated with a physical functioning score improvement 19.4 points (95% confidence interval 7.7, 31.2) greater than the improvement in grades 0-3, but BMI was unrelated to change in physical functioning. CONCLUSION: Improvements in physical functioning following THA for OA are sustained in the long term and are more frequent in patients with more severe radiographic features preoperatively. We found no indication that patients who are overweight benefit less from THA, but further evidence is needed on the prognostic influence of more severe obesity

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More information

Published date: 2007
Keywords: women, overweight, osteoarthritis, body mass index, methods, longitudinal studies, health, obesity, bone, prognosis, mental health, hip, comorbidity
Organisations: Community Clinical Sciences, Dev Origins of Health & Disease

Identifiers

Local EPrints ID: 61035
URI: http://eprints.soton.ac.uk/id/eprint/61035
ISSN: 0893-7524
PURE UUID: 8955821e-0640-49fb-ab90-62bac4e1e688
ORCID for D. Coggon: ORCID iD orcid.org/0000-0003-1930-3987
ORCID for I. Reading: ORCID iD orcid.org/0000-0002-1457-6532
ORCID for C. Cooper: ORCID iD orcid.org/0000-0003-3510-0709

Catalogue record

Date deposited: 04 Sep 2008
Last modified: 08 Jan 2022 02:49

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Contributors

Author: J. Cushnaghan
Author: D. Coggon ORCID iD
Author: I. Reading ORCID iD
Author: P. Croft
Author: P. Byng
Author: K. Cox
Author: P. Dieppe
Author: C. Cooper ORCID iD

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