Antiplatelet effects of licking an aspirin tablet can be detected by thrombelastography
Antiplatelet effects of licking an aspirin tablet can be detected by thrombelastography
Aspirin is a cornerstone of treatment in cardiovascular disease. However, individual responses vary and hyporesponsiveness has been associated with poor outcomes following percutaneous intervention. Point of care assays for detecting the effects of aspirin in individual patients would therefore be useful. Thrombelastography has been shown to correlate with optical aggregation in the assessment of antiplatelet therapies and is suitable for use as a point of care assay. We demonstrate the ability of thrombelastography to detect the profound effects of even the tiny doses of aspirin obtained by licking an aspirin tablet
cardiovascular, thrombelastography, aspirin, responses, cardiovascular-disease, therapy, letter, disease, cardiovascular disease
62-63
Hobson, A.R.
8618bc75-f62f-4ac6-be38-b090dea18c91
Dawkins, K.D.
528a45bb-0158-4dbf-af28-2a64d43244e3
Curzen, N.P.
70f3ea49-51b1-418f-8e56-8210aef1abf4
2008
Hobson, A.R.
8618bc75-f62f-4ac6-be38-b090dea18c91
Dawkins, K.D.
528a45bb-0158-4dbf-af28-2a64d43244e3
Curzen, N.P.
70f3ea49-51b1-418f-8e56-8210aef1abf4
Hobson, A.R., Dawkins, K.D. and Curzen, N.P.
(2008)
Antiplatelet effects of licking an aspirin tablet can be detected by thrombelastography.
Acute Cardiac Care, 10 (1), .
(doi:10.1080/17482940701385203).
Abstract
Aspirin is a cornerstone of treatment in cardiovascular disease. However, individual responses vary and hyporesponsiveness has been associated with poor outcomes following percutaneous intervention. Point of care assays for detecting the effects of aspirin in individual patients would therefore be useful. Thrombelastography has been shown to correlate with optical aggregation in the assessment of antiplatelet therapies and is suitable for use as a point of care assay. We demonstrate the ability of thrombelastography to detect the profound effects of even the tiny doses of aspirin obtained by licking an aspirin tablet
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Published date: 2008
Keywords:
cardiovascular, thrombelastography, aspirin, responses, cardiovascular-disease, therapy, letter, disease, cardiovascular disease
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Local EPrints ID: 61219
URI: http://eprints.soton.ac.uk/id/eprint/61219
ISSN: 1748-2941
PURE UUID: 90ed2d31-f7e8-4354-8374-206d14f7d574
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Date deposited: 02 Sep 2008
Last modified: 16 Mar 2024 03:45
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Author:
A.R. Hobson
Author:
K.D. Dawkins
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