Management of disorders of ovulation [In special issue: Women and the ovary]
Management of disorders of ovulation [In special issue: Women and the ovary]
This review article evaluates the management of disorders of ovulation by first examining the specific conditions covering hypothalamic disorders, polycystic ovary syndrome and hyperprolactinaemia. Treatment options for disorders of ovulation depend on the clinical presentation, the underlying cause and the woman's wishes. Those who seek fertility require treatment to induce ovulation, and this treatment should be offered in conjunction with assessment of other factors relevant to fertility, including semen analysis and the exclusion of pelvic pathology. The uses of clomiphene citrate, gonadotrophins, gonadotrophin releasing hormone (GnRH), metformin, laparoscopic surgery and in vitro fertilization (IVF) are discussed. Ovulation should not be induced in women who do not wish to conceive. These women usually seek a diagnosis and cycle control. This is best achieved using cyclical progestogens or an oestrogen-progestogen pill, and treatment choice depends on the woman's oestrogen status and her contraceptive needs. The final section concentrates on adverse outcomes of induction ovulation including multiple pregnancy, ovarian hyperstimulation syndrome (OHSS) and ovarian carcinoma.
ovulation disorder, clomiphene, metformin, in vitro fertilization, polycystic ovary syndrome
115-118
Ingamells, Susan
8d491be5-b202-4af2-8c7b-69e6f6729e37
Cameron, Iain T.
f7595539-efa6-4687-b161-e1e93ff710f2
1 May 2006
Ingamells, Susan
8d491be5-b202-4af2-8c7b-69e6f6729e37
Cameron, Iain T.
f7595539-efa6-4687-b161-e1e93ff710f2
Ingamells, Susan and Cameron, Iain T.
(2006)
Management of disorders of ovulation [In special issue: Women and the ovary].
Women's Health Medicine, 3 (3), .
(doi:10.1383/wohm.2006.3.3.115).
Abstract
This review article evaluates the management of disorders of ovulation by first examining the specific conditions covering hypothalamic disorders, polycystic ovary syndrome and hyperprolactinaemia. Treatment options for disorders of ovulation depend on the clinical presentation, the underlying cause and the woman's wishes. Those who seek fertility require treatment to induce ovulation, and this treatment should be offered in conjunction with assessment of other factors relevant to fertility, including semen analysis and the exclusion of pelvic pathology. The uses of clomiphene citrate, gonadotrophins, gonadotrophin releasing hormone (GnRH), metformin, laparoscopic surgery and in vitro fertilization (IVF) are discussed. Ovulation should not be induced in women who do not wish to conceive. These women usually seek a diagnosis and cycle control. This is best achieved using cyclical progestogens or an oestrogen-progestogen pill, and treatment choice depends on the woman's oestrogen status and her contraceptive needs. The final section concentrates on adverse outcomes of induction ovulation including multiple pregnancy, ovarian hyperstimulation syndrome (OHSS) and ovarian carcinoma.
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Published date: 1 May 2006
Keywords:
ovulation disorder, clomiphene, metformin, in vitro fertilization, polycystic ovary syndrome
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Local EPrints ID: 61239
URI: http://eprints.soton.ac.uk/id/eprint/61239
ISSN: 1744-1870
PURE UUID: 30c0cc38-8a5f-484b-8184-89d986d7deda
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Date deposited: 09 Oct 2008
Last modified: 16 Mar 2024 03:00
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Author:
Susan Ingamells
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