The significance of low urinary sodium excretion in Ileostomy patients

Ng, D.H.L., Wootton, S.A., Jackson, A.A. and Stroud, M.A. (2006) The significance of low urinary sodium excretion in Ileostomy patients. Gut, 55 (Supplement 2), A12-A13.

Abstract

Background: Chronic sodium (Na) and water depletion is well recognised in colectomy patients with ileostomies. The withdrawal of Na from intravenous nutrition has been shown to inhibit retention of nitrogen (N) and calcium (Ca) in underweight adults leading to the failure of lean tissue and bone mineral repletion.1 This study examined the relationships between urinary Na excretion and body mass index (BMI), lean body mass (LBM), urinary excretions of N, Ca, and Mg, and bone mineral density (BMD) in ileostomy patients.
Methods: Urinary excretions of Na, N, Ca, and Mg were measured along with BMI and LBM (using bioelectrical impedance analysis) in 59 ileostomy patients. Urinary Na below 100 mmol/day was considered to be low compared to chemical pathology reference values. BMD of lumbar spine (LS) and right femoral neck (FN) were also determined using DEXA in these subjects. Results are presented in median (range).
Results: Median urinary Na excretion was 73 mmol/day (5–456). Thirty seven (62.7%) had low urinary Na and 22 (37.3%) had normal urinary Na.Conclusions: Ileostomy patients who have Na depletion are not only at risk of renal impairment from chronic dehydration but may also have compromised nitrogen and mineral status. These patients, who are often asymptomatic, are therefore at risk of subclinical malnutrition and osteoporosis.

This record has no associated files available for download.

Contributors

Download statistics