The University of Southampton
University of Southampton Institutional Repository

Fatty acids and immune function: new insights into mechanisms

Yaqoob, Parveen and Calder, Philip C. (2007) Fatty acids and immune function: new insights into mechanisms British Journal of Nutrition, 98, (Supplement S1), S41-S45. (doi:10.1017/S0007114507832995).

Record type: Article


Fatty acids are known to play diverse roles in immune cells. They are important as a source of energy, as structural components of cell membranes, as signaling molecules and as precursors for the synthesis of eicosanoids and similar mediators. Recent research has suggested that the localization and organisation of fatty acids into distinct cellular pools has a direct influence on the behaviour of a number of proteins involved in immune cell activation, including those associated with T cell responses, antigen presentation and fatty acid-derived inflammatory mediator production. This article reviews these studies and places them in the context of existing literature in the field. These studies indicate the existence of several novel mechanisms by which altered fatty acid availability can modulate immune responses and impact upon clinical outcomes.

Full text not available from this repository.

More information

Published date: October 2007
Keywords: fatty acid, fish oil, omega-3, eicosanoid, lipid raft, t cell, lymphocyte, antigen presentation, lipid body, inflammation


Local EPrints ID: 61627
ISSN: 0007-1145
PURE UUID: cbe09692-85d6-403e-ab2d-8421c609d34a

Catalogue record

Date deposited: 07 Oct 2008
Last modified: 17 Jul 2017 14:21

Export record



Author: Parveen Yaqoob

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton:

ePrints Soton supports OAI 2.0 with a base URL of

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.