The University of Southampton
University of Southampton Institutional Repository

Risk factors for knee osteoarthritis in Japanese men: a case-control study

Record type: Article

Risk of knee osteoarthritis (OA) was assessed in a population-based case-control study of Japanese men. The study covered three health districts in Wakayama and Osaka prefectures, Japan. Subjects were male individuals >or=45 years old diagnosed radiographically with knee OA, and who did not display any established causes of secondary OA. Controls selected randomly from the general population were individually matched to cases for age, sex, and residential district. Subjects were interviewed using structured questionnaires to determine medical history, physical activity, socio-economic factors, and occupation. Interviews were obtained from 37 cases and 37 controls. In univariate analysis, heaviest weight in the past and physical work such as factory, construction, agricultural, or fishery work as the principal occupation significantly raised the risk of male knee OA (P<0.05). Odds ratios (OR) were determined using conditional logistic regression analysis mutually adjusted for potential risk factors using the results of univariate analysis. Heaviest weight in the past (OR 6.01, 95% confidence interval (CI) 1.18-30.5, P<0.05), past knee injury (OR 6.25, 95% CI 1.13-34.5, P<0.05), and physical work as the principal occupation (OR 6.20, 95% CI 1.40-27.5, P<0.05) represented independent factors associated with knee OA after controlling for other risk factors. Physical work is associated with knee OA, demonstrating the influence of working activity on the development of OA. The present study suggests that risk factors for knee OA in men resemble those in women.

Full text not available from this repository.

Citation

Yoshimura, Noriko, Kinoshita, Hirofumi, Hori, Noriaki, Nishioka, Taira, Ryujin, Masahiko, Mantani, Yoshihiko, Miyake, Mariko, Takeshita, Tatsuya, Ichinose, Masao, Yoshiida, Munehito, Oka, Hiroyuki, Kawaguchi, Hiroshi, Nakamura, Kozo and Cooper, Cyrus (2006) Risk factors for knee osteoarthritis in Japanese men: a case-control study Modern Rheumatology, 16, (1), pp. 24-29. (doi:10.1007/s10165-005-0450-6).

More information

Published date: February 2006
Keywords: bone, activity, weight, health, questionnaires, male, men, risk factors, development, japan, women, odds ratio, socioeconomic factors, analysis, injuries, osteoarthritis, regression analysis, case-control studies, risk

Identifiers

Local EPrints ID: 61634
URI: http://eprints.soton.ac.uk/id/eprint/61634
PURE UUID: 2844ebdb-e0b5-4698-a4a5-90c712706a98

Catalogue record

Date deposited: 01 Oct 2008
Last modified: 17 Jul 2017 14:21

Export record

Altmetrics

Contributors

Author: Noriko Yoshimura
Author: Hirofumi Kinoshita
Author: Noriaki Hori
Author: Taira Nishioka
Author: Masahiko Ryujin
Author: Yoshihiko Mantani
Author: Mariko Miyake
Author: Tatsuya Takeshita
Author: Masao Ichinose
Author: Munehito Yoshiida
Author: Hiroyuki Oka
Author: Hiroshi Kawaguchi
Author: Kozo Nakamura
Author: Cyrus Cooper

University divisions


Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×