The University of Southampton
University of Southampton Institutional Repository

A homeopathic and conventional treatment for acute respiratory and ear complaints: a comparative study on outcome in a primary care setting

A homeopathic and conventional treatment for acute respiratory and ear complaints: a comparative study on outcome in a primary care setting
A homeopathic and conventional treatment for acute respiratory and ear complaints: a comparative study on outcome in a primary care setting
Background: the aim of this study was to assess the effectiveness of homeopathy compared to conventional treatment in acute respiratory and ear complaints in a primary care setting.

Methods: the study was designed as an international, multi-centre, comparative cohort study of non-randomised design. Patients, presenting themselves with at least one chief complaint: acute (? 7 days) runny nose, sore throat, ear pain, sinus pain or cough, were recruited at 57 primary care practices in Austria (8), Germany (8), the Netherlands (7), Russia (6), Spain (6), Ukraine (4), United Kingdom (10) and the USA (8) and given either homeopathic or conventional treatment. Therapy outcome was measured by using the response rate, defined as the proportion of patients experiencing 'complete recovery' or 'major improvement' in each treatment group. The primary outcome criterion was the response rate after 14 days of therapy.

Results: data of 1,577 patients were evaluated in the full analysis set of which 857 received homeopathic (H) and 720 conventional (C) treatment. The majority of patients in both groups reported their outcome after 14 days of treatment as complete recovery or major improvement (H: 86.9%; C: 86.0%; p = 0.0003 for non-inferiority testing). In the per-protocol set (H: 576 and C: 540 patients) similar results were obtained (H: 87.7%; C: 86.9%; p = 0.0019). Further subgroup analysis of the full analysis set showed no differences of response rates after 14 days in children (H: 88.5%; C: 84.5%) and adults (H: 85.6%; C: 86.6%). The unadjusted odds ratio (OR) of the primary outcome criterion was 1.40 (0.89–2.22) in children and 0.92 (0.63–1.34) in adults. Adjustments for demographic differences at baseline did not significantly alter the OR. The response rates after 7 and 28 days also showed no significant differences between both treatment groups. However, onset of improvement within the first 7 days after treatment was significantly faster upon homeopathic treatment both in children (p = 0.0488) and adults (p = 0.0001). Adverse drug reactions occurred more frequently in adults of the conventional group than in the homeopathic group (C: 7.6%; H: 3.1%, p = 0.0032), whereas in children the occurrence of adverse drug reactions was not significantly different (H: 2.0%; C: 2.4%, p = 0.7838).

Conclusion: in primary care, homeopathic treatment for acute respiratory and ear complaints was not inferior to conventional treatment
treatment, comparative study
1472-6882
7-18
Haidvogl, M.
2bafdec7-7948-4847-86b8-7af91c7188f8
Riley, D.
bc54aedc-72a9-482e-87b2-326bfddacbd8
Brien, S.
4e8e97cd-7bc3-4efd-857e-20790040b80f
Jong, M.
de8f0208-3a01-4002-be58-3c13856d56d5
Fischer, M.
bdf00760-3e09-4caa-9c4d-bc23de19ada9
Lewith, G.
0fc483fa-f17b-47c5-94d9-5c15e65a7625
Haidvogl, M.
2bafdec7-7948-4847-86b8-7af91c7188f8
Riley, D.
bc54aedc-72a9-482e-87b2-326bfddacbd8
Brien, S.
4e8e97cd-7bc3-4efd-857e-20790040b80f
Jong, M.
de8f0208-3a01-4002-be58-3c13856d56d5
Fischer, M.
bdf00760-3e09-4caa-9c4d-bc23de19ada9
Lewith, G.
0fc483fa-f17b-47c5-94d9-5c15e65a7625

Haidvogl, M., Riley, D., Brien, S., Jong, M., Fischer, M. and Lewith, G. (2007) A homeopathic and conventional treatment for acute respiratory and ear complaints: a comparative study on outcome in a primary care setting. BMC Complementary and Alternative Medicine, 7 (2), 7-18. (doi:10.1186/1472-6882-7-7).

Record type: Article

Abstract

Background: the aim of this study was to assess the effectiveness of homeopathy compared to conventional treatment in acute respiratory and ear complaints in a primary care setting.

Methods: the study was designed as an international, multi-centre, comparative cohort study of non-randomised design. Patients, presenting themselves with at least one chief complaint: acute (? 7 days) runny nose, sore throat, ear pain, sinus pain or cough, were recruited at 57 primary care practices in Austria (8), Germany (8), the Netherlands (7), Russia (6), Spain (6), Ukraine (4), United Kingdom (10) and the USA (8) and given either homeopathic or conventional treatment. Therapy outcome was measured by using the response rate, defined as the proportion of patients experiencing 'complete recovery' or 'major improvement' in each treatment group. The primary outcome criterion was the response rate after 14 days of therapy.

Results: data of 1,577 patients were evaluated in the full analysis set of which 857 received homeopathic (H) and 720 conventional (C) treatment. The majority of patients in both groups reported their outcome after 14 days of treatment as complete recovery or major improvement (H: 86.9%; C: 86.0%; p = 0.0003 for non-inferiority testing). In the per-protocol set (H: 576 and C: 540 patients) similar results were obtained (H: 87.7%; C: 86.9%; p = 0.0019). Further subgroup analysis of the full analysis set showed no differences of response rates after 14 days in children (H: 88.5%; C: 84.5%) and adults (H: 85.6%; C: 86.6%). The unadjusted odds ratio (OR) of the primary outcome criterion was 1.40 (0.89–2.22) in children and 0.92 (0.63–1.34) in adults. Adjustments for demographic differences at baseline did not significantly alter the OR. The response rates after 7 and 28 days also showed no significant differences between both treatment groups. However, onset of improvement within the first 7 days after treatment was significantly faster upon homeopathic treatment both in children (p = 0.0488) and adults (p = 0.0001). Adverse drug reactions occurred more frequently in adults of the conventional group than in the homeopathic group (C: 7.6%; H: 3.1%, p = 0.0032), whereas in children the occurrence of adverse drug reactions was not significantly different (H: 2.0%; C: 2.4%, p = 0.7838).

Conclusion: in primary care, homeopathic treatment for acute respiratory and ear complaints was not inferior to conventional treatment

Text
1472-6882-7-7.pdf - Version of Record
Available under License Other.
Download (324kB)

More information

Published date: 2 March 2007
Keywords: treatment, comparative study
Organisations: Faculty of Medicine

Identifiers

Local EPrints ID: 61808
URI: http://eprints.soton.ac.uk/id/eprint/61808
ISSN: 1472-6882
PURE UUID: c83667ab-eee4-4b11-af67-7600b34453e8

Catalogue record

Date deposited: 04 Sep 2008
Last modified: 16 Dec 2019 19:16

Export record

Altmetrics

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×