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Electrical treatment of tibial non-union: a prospective, randomised, double-blind trial

Simonis, R.B., Parnell, E.J., Ray, P.S. and Peacock, J.L. (2003) Electrical treatment of tibial non-union: a prospective, randomised, double-blind trial Injury, 34, (5), pp. 357-362.

Record type: Article


Electrical stimulation in the treatment of bony non-union has been used in different forms for many years. However, there is still a lot of uncertainty about its efficacy. We, therefore, undertook a prospective, randomised, double-blind trial to try and determine its effect. Over a period of 5 years, 34 consecutive patients with a tibial non-union met our "criteria for inclusion". Each patient had an oblique fibular osteotomy, followed by a unilateral external fixator. They were then randomly allocated one of two machines. Group 1, the active group, received electrical stimulation from an active machine. Group 2, the dummy group, had an identical machine but without any current passing through the active coils. They were then followed up for 6 months and evaluated clinically and radiologically for bony union. Unfortunately, there was by chance, an imbalance in smoking habit between the two groups. The union rate in the subgroup that smoked was 75% (6/8) in the active group as compared to 46% (6/13) in the dummy group. The active group of non-smokers had 100% (10/10) union rate, compared to 67% (2/3) in the dummy group. Overall 24 out of the 34 patients progressed to union. Out of 18, 16 (89%) in the active group showed bony union as compared to 8/16 (50%) in the dummy. There was, thus, a statistically significant positive association between tibial union and electrical stimulation (odds ratio 8, 95% CI: 1.5-41, P=0.02)

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Published date: May 2003
Keywords: trial, osteotomy, efficacy, controlled-trial, radiography, stimulation, methods, odds ratio, smoking, adult, patients, double-blind trial, double-blind, clinical-trial, male, nhs, humans, therapy, adolescent, female, electric stimulation therapy, double-blind method, electromagnetic fields, ununited, hospitals, controlled trial, middle aged, tibial fractures, prospective studies, treatment outcome, fractures, treatment


Local EPrints ID: 62120
ISSN: 0020-1383
PURE UUID: 2ba576ae-734c-4d53-8ea5-d16584fb026f

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Date deposited: 10 Sep 2008
Last modified: 17 Jul 2017 14:21

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Author: R.B. Simonis
Author: E.J. Parnell
Author: P.S. Ray
Author: J.L. Peacock

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