The University of Southampton
University of Southampton Institutional Repository

Prescribing of the antidepressant duloxetine: Can local clinical audit findings facilitate medicines management decisions?

Prescribing of the antidepressant duloxetine: Can local clinical audit findings facilitate medicines management decisions?
Prescribing of the antidepressant duloxetine: Can local clinical audit findings facilitate medicines management decisions?
Introduction. Discussions regarding the inclusion of a new antidepressant within local formulary lists and prescribing guidelines may be facilitated by audits of local prescribing practice, conducted some months after the drug first becomes available for clinical use.
Method. Development of five audit standards and retrospective case-note review of prescribing recommendations for the serotonin-noradrenaline reuptake inhibitor duloxetine, made in five local outpatient clinics.
Results. Follow-up data were available for audit in 27 of 43 sets of medical notes. In the majority of patients (84%), the primary diagnosis was recurrent unipolar depressive disorder, the current episode having proven resistant to treatment with two other antidepressants. Where comments were made, notes indicated that 81% of patients that received duloxetine had improved and 94% had tolerated it without reported problems.
Conclusions. In this sample, duloxetine prescribing in the first months after it became available appeared to occur within an appropriate patient group. Prospective evaluations in other clinical samples are warranted.
prescribing, audit, paroxetine, placebo, controlled trial, double-blind, major depressive disorder, medicines management, duloxetine
156-159
Ajel, K.
68013000-04dd-4ecd-ac40-71beac545318
Bhogal, K.
9cac9901-a82d-4ded-aecc-bb20858efbe2
Baldwin, D.
1beaa192-0ef1-4914-897a-3a49fc2ed15e
Ajel, K.
68013000-04dd-4ecd-ac40-71beac545318
Bhogal, K.
9cac9901-a82d-4ded-aecc-bb20858efbe2
Baldwin, D.
1beaa192-0ef1-4914-897a-3a49fc2ed15e

Ajel, K., Bhogal, K. and Baldwin, D. (2008) Prescribing of the antidepressant duloxetine: Can local clinical audit findings facilitate medicines management decisions? International Journal of Psychiatry in Clinical Practice, 12 (2), 156-159. (doi:10.1080/13651500701799052).

Record type: Article

Abstract

Introduction. Discussions regarding the inclusion of a new antidepressant within local formulary lists and prescribing guidelines may be facilitated by audits of local prescribing practice, conducted some months after the drug first becomes available for clinical use.
Method. Development of five audit standards and retrospective case-note review of prescribing recommendations for the serotonin-noradrenaline reuptake inhibitor duloxetine, made in five local outpatient clinics.
Results. Follow-up data were available for audit in 27 of 43 sets of medical notes. In the majority of patients (84%), the primary diagnosis was recurrent unipolar depressive disorder, the current episode having proven resistant to treatment with two other antidepressants. Where comments were made, notes indicated that 81% of patients that received duloxetine had improved and 94% had tolerated it without reported problems.
Conclusions. In this sample, duloxetine prescribing in the first months after it became available appeared to occur within an appropriate patient group. Prospective evaluations in other clinical samples are warranted.

Full text not available from this repository.

More information

Published date: 2008
Keywords: prescribing, audit, paroxetine, placebo, controlled trial, double-blind, major depressive disorder, medicines management, duloxetine

Identifiers

Local EPrints ID: 62228
URI: https://eprints.soton.ac.uk/id/eprint/62228
PURE UUID: 9f8eb226-9c5d-46d1-b4ae-c56c3512324e

Catalogue record

Date deposited: 04 Sep 2008
Last modified: 13 Mar 2019 20:27

Export record

Altmetrics

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of https://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×