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How effective are current drug treatments for anxiety disorders, and how could they be improved?

How effective are current drug treatments for anxiety disorders, and how could they be improved?
How effective are current drug treatments for anxiety disorders, and how could they be improved?
Although there are many psychotropic drugs and psychotherapies available for the treatment of patients with anxiety disorders, overall clinical outcomes and the standard of care for most patients with these common, persistent and impairing illnesses are usually far from optimal. The disorders typically follow a chronic or recurring course in which full symptomatic remission is uncommon; they are associated with the temporal accumulation of comorbid disorders and with an increased suicide risk; and treatment responsiveness may diminish over time. This chapter examines the efficacy of current pharmacological treatments in the three main anxiety disorders – generalised anxiety disorder (GAD), panic disorder andsocial anxiety disorder (social phobia) – and summarises how clinical outcomes might be improved by anumber of alternative approaches, including the enhanced use of existing treatments, modifications toexisting psychotropic drugs and the development of new targets for anxiolytic pharmacotherapy. It also describes how advances in genetics and neuroscience might lead towards more individualised drug treatments, whilst recognising that theoretical treatment advances can only improve outcomes if used rationally, in collaboration with the patient.
treatment, anxiety disorders
9780444530653
395-411
Elsevier
Baldwin, David S.
1beaa192-0ef1-4914-897a-3a49fc2ed15e
Garner, Matthew J.
3221c5b3-b951-4fec-b456-ec449e4ce072
Blanchard, Robert
Blanchard, D. Caroline
Griebel, Guy
Nutt, David
Baldwin, David S.
1beaa192-0ef1-4914-897a-3a49fc2ed15e
Garner, Matthew J.
3221c5b3-b951-4fec-b456-ec449e4ce072
Blanchard, Robert
Blanchard, D. Caroline
Griebel, Guy
Nutt, David

Baldwin, David S. and Garner, Matthew J. (2008) How effective are current drug treatments for anxiety disorders, and how could they be improved? In, Blanchard, Robert, Blanchard, D. Caroline, Griebel, Guy and Nutt, David (eds.) Handbook of Anxiety and Fear. (Handbook of Behavioral Neuroscience, , (doi:10.1016/S1569-7339(07)00001), 17) Amsterdam, The Netherlands. Elsevier, pp. 395-411. (doi:10.1016/S1569-7339(07)00001).

Record type: Book Section

Abstract

Although there are many psychotropic drugs and psychotherapies available for the treatment of patients with anxiety disorders, overall clinical outcomes and the standard of care for most patients with these common, persistent and impairing illnesses are usually far from optimal. The disorders typically follow a chronic or recurring course in which full symptomatic remission is uncommon; they are associated with the temporal accumulation of comorbid disorders and with an increased suicide risk; and treatment responsiveness may diminish over time. This chapter examines the efficacy of current pharmacological treatments in the three main anxiety disorders – generalised anxiety disorder (GAD), panic disorder andsocial anxiety disorder (social phobia) – and summarises how clinical outcomes might be improved by anumber of alternative approaches, including the enhanced use of existing treatments, modifications toexisting psychotropic drugs and the development of new targets for anxiolytic pharmacotherapy. It also describes how advances in genetics and neuroscience might lead towards more individualised drug treatments, whilst recognising that theoretical treatment advances can only improve outcomes if used rationally, in collaboration with the patient.

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More information

Published date: March 2008
Keywords: treatment, anxiety disorders

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Local EPrints ID: 62293
URI: https://eprints.soton.ac.uk/id/eprint/62293
ISBN: 9780444530653
PURE UUID: 262eef3e-456d-42da-8b4d-60467b3b863e

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Date deposited: 17 Apr 2009
Last modified: 13 Mar 2019 20:27

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