Idiopathic juxtafoveolar retinal telangiectasis in monozygotic twins
Idiopathic juxtafoveolar retinal telangiectasis in monozygotic twins
Monozygotic twins (aged 63 years old), with group-2A idiopathic juxtafoveolar retinal telangiectasia (JXT), underwent clinical examination, fluorescein angiography (FA) and optical coherence tomography (OCT). Twin 1: Right fundus showed right-angled venules temporal to the fovea; FA demonstrated retino-retinal anastomosis and intraretinal leakage. Twin 2: Fundoscopy revealed right-angled venules in both eyes. OCT demonstrated foveal cysts in all eyes. This is the third set of monozygotic twins with group-2A JXT that has been reported in the literature, further supporting a genetic predisposition for JXT. The twin who smoked had more severe disease, suggesting that smoking is a risk factor for progression. OCT is useful in the detection and monitoring of these patients.
Group-2A JXT is characterised by bilateral regions of retinal thickening temporal to the fovea with minimal exudation.1 Gass and Blodi described five stages of group-2A JXT.1 OCT clearly depicts the involvement of the intraretinal and subretinal spaces in this condition. Intraretinal cysts, lamellar hole, subretinal fibrosis and speckled intraretinal yellow-red hyper-reflectivity have been reported.2
eye
1729-1730
Hannan, S.R.
59e67ba3-13ba-4ae6-a1d3-80b1f8c0292f
Madhusudhana, K.C.
38366182-3e2e-43fe-9fdd-d437bf7907d7
Rennie, C.
35078ab5-7248-40b2-8a50-b90d6d1394bc
Lotery, A.J.
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514
2007
Hannan, S.R.
59e67ba3-13ba-4ae6-a1d3-80b1f8c0292f
Madhusudhana, K.C.
38366182-3e2e-43fe-9fdd-d437bf7907d7
Rennie, C.
35078ab5-7248-40b2-8a50-b90d6d1394bc
Lotery, A.J.
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514
Hannan, S.R., Madhusudhana, K.C., Rennie, C. and Lotery, A.J.
(2007)
Idiopathic juxtafoveolar retinal telangiectasis in monozygotic twins.
British Journal of Ophthalmology, 91 (12), .
(doi:10.1136/bjo.2007.115675).
Abstract
Monozygotic twins (aged 63 years old), with group-2A idiopathic juxtafoveolar retinal telangiectasia (JXT), underwent clinical examination, fluorescein angiography (FA) and optical coherence tomography (OCT). Twin 1: Right fundus showed right-angled venules temporal to the fovea; FA demonstrated retino-retinal anastomosis and intraretinal leakage. Twin 2: Fundoscopy revealed right-angled venules in both eyes. OCT demonstrated foveal cysts in all eyes. This is the third set of monozygotic twins with group-2A JXT that has been reported in the literature, further supporting a genetic predisposition for JXT. The twin who smoked had more severe disease, suggesting that smoking is a risk factor for progression. OCT is useful in the detection and monitoring of these patients.
Group-2A JXT is characterised by bilateral regions of retinal thickening temporal to the fovea with minimal exudation.1 Gass and Blodi described five stages of group-2A JXT.1 OCT clearly depicts the involvement of the intraretinal and subretinal spaces in this condition. Intraretinal cysts, lamellar hole, subretinal fibrosis and speckled intraretinal yellow-red hyper-reflectivity have been reported.2
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Published date: 2007
Keywords:
eye
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Local EPrints ID: 62396
URI: http://eprints.soton.ac.uk/id/eprint/62396
ISSN: 0007-1161
PURE UUID: e6cf05c0-3315-41e5-809b-d4b5975e242f
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Date deposited: 09 Sep 2008
Last modified: 16 Mar 2024 03:31
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Author:
S.R. Hannan
Author:
K.C. Madhusudhana
Author:
C. Rennie
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