Retinal pigment epithelial tear following intravitreal bevacizumab for choroidal neovascular membrane due to age-related macular degeneration
Retinal pigment epithelial tear following intravitreal bevacizumab for choroidal neovascular membrane due to age-related macular degeneration
Retinal pigment epithelium (RPE) tears are an uncommon but visually damaging complication of pigment epithelial detachment (PED), caused by weak atrophic margins of chronic PED and contraction of sub-RPE fibrovascular scar tissue. RPE tears can occur spontaneously or following treatment of the choroidal neovascular (CNV) membrane. There have been reports of RPE tears following laser photocoagulation, transpupillary thermotherapy, photodynamic therapy with or without combined intravitreal triamcinolone and intravitreal Macugen. We report a case of a patient with PED with submacular haemorrhage and occult CNV who developed an RPE tear following intravitreal bevacizumab (Avastin).
macular degeneration, intravitreal bevacizumab, pigment, therapy, eye
977-978
Hannan, S.R.
59e67ba3-13ba-4ae6-a1d3-80b1f8c0292f
Madhusudhana, K.C.
38366182-3e2e-43fe-9fdd-d437bf7907d7
Lotery, A.J.
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514
Newsom, R.S.B.
61a941d6-44a3-4c05-aff5-7f5450c5b75b
2007
Hannan, S.R.
59e67ba3-13ba-4ae6-a1d3-80b1f8c0292f
Madhusudhana, K.C.
38366182-3e2e-43fe-9fdd-d437bf7907d7
Lotery, A.J.
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514
Newsom, R.S.B.
61a941d6-44a3-4c05-aff5-7f5450c5b75b
Hannan, S.R., Madhusudhana, K.C., Lotery, A.J. and Newsom, R.S.B.
(2007)
Retinal pigment epithelial tear following intravitreal bevacizumab for choroidal neovascular membrane due to age-related macular degeneration.
British Journal of Ophthalmology, 91 (7), .
(doi:10.1136/bjo.2006.101899).
Abstract
Retinal pigment epithelium (RPE) tears are an uncommon but visually damaging complication of pigment epithelial detachment (PED), caused by weak atrophic margins of chronic PED and contraction of sub-RPE fibrovascular scar tissue. RPE tears can occur spontaneously or following treatment of the choroidal neovascular (CNV) membrane. There have been reports of RPE tears following laser photocoagulation, transpupillary thermotherapy, photodynamic therapy with or without combined intravitreal triamcinolone and intravitreal Macugen. We report a case of a patient with PED with submacular haemorrhage and occult CNV who developed an RPE tear following intravitreal bevacizumab (Avastin).
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Published date: 2007
Keywords:
macular degeneration, intravitreal bevacizumab, pigment, therapy, eye
Identifiers
Local EPrints ID: 62397
URI: http://eprints.soton.ac.uk/id/eprint/62397
ISSN: 0007-1161
PURE UUID: cca0314c-05dc-4a52-b5a5-3d426c0ef771
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Date deposited: 09 Sep 2008
Last modified: 16 Mar 2024 03:31
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Author:
S.R. Hannan
Author:
K.C. Madhusudhana
Author:
R.S.B. Newsom
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