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Schizophrenia and deliberate self-harm: a systematic review of risk factors

Schizophrenia and deliberate self-harm: a systematic review of risk factors
Schizophrenia and deliberate self-harm: a systematic review of risk factors
Deliberate self-harm (DSH) is a strong predictor of suicide in schizophrenia. The aim of this review was to identify risk factors for DSH in schizophrenia. This systematic review of the international literature examined cohort and case-control studies of patients with schizophrenia or related diagnoses that reported DSH as an outcome. Studies were identified by searching electronic databases and reference lists, and by consulting international experts. Fourteen studies met the eligibility criteria. Of the 29 variables examined by two or more studies, five (past or recent suicidal ideation, previous DSH, past depressive episode, drug abuse or dependence, and higher mean number of psychiatric admissions) were associated with an increased risk of DSH, and one (unemployment) was associated with a reduced risk. Schizophrenic patients with these risk factors need careful follow-up and monitoring, with treatment of any associated comorbid depression or drug abuse. Large, prospective studies of DSH in schizophrenia are needed to further define risk factors and to build on the findings of this review.
meta-analysis, prospective studies, risk factors, follow-up studies, treatment, review, research, patients, adult, schizophrenia, depression, dsh, male, humans, epidemiology
0363-0234
50-62
Haw, Camilla
7aaad16c-ad16-4786-8de5-11fc6d0a4520
Hawton, Keith
9f57477d-ec55-44f3-b172-20872ed9d02a
Sutton, Lesley
87bfb557-5fce-4101-a790-c8b40aed17b0
Sinclair, Julia
be3e54d5-c6da-4950-b0ba-3cb8cdcab13c
Deeks, Jonathan
998ba22f-f7f2-46bf-891f-02ec367881cf
Haw, Camilla
7aaad16c-ad16-4786-8de5-11fc6d0a4520
Hawton, Keith
9f57477d-ec55-44f3-b172-20872ed9d02a
Sutton, Lesley
87bfb557-5fce-4101-a790-c8b40aed17b0
Sinclair, Julia
be3e54d5-c6da-4950-b0ba-3cb8cdcab13c
Deeks, Jonathan
998ba22f-f7f2-46bf-891f-02ec367881cf

Haw, Camilla, Hawton, Keith, Sutton, Lesley, Sinclair, Julia and Deeks, Jonathan (2005) Schizophrenia and deliberate self-harm: a systematic review of risk factors. Suicide and Life-Threatening Behavior, 35 (1), 50-62. (doi:10.1521/suli.35.1.50.59260).

Record type: Article

Abstract

Deliberate self-harm (DSH) is a strong predictor of suicide in schizophrenia. The aim of this review was to identify risk factors for DSH in schizophrenia. This systematic review of the international literature examined cohort and case-control studies of patients with schizophrenia or related diagnoses that reported DSH as an outcome. Studies were identified by searching electronic databases and reference lists, and by consulting international experts. Fourteen studies met the eligibility criteria. Of the 29 variables examined by two or more studies, five (past or recent suicidal ideation, previous DSH, past depressive episode, drug abuse or dependence, and higher mean number of psychiatric admissions) were associated with an increased risk of DSH, and one (unemployment) was associated with a reduced risk. Schizophrenic patients with these risk factors need careful follow-up and monitoring, with treatment of any associated comorbid depression or drug abuse. Large, prospective studies of DSH in schizophrenia are needed to further define risk factors and to build on the findings of this review.

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More information

Published date: February 2005
Keywords: meta-analysis, prospective studies, risk factors, follow-up studies, treatment, review, research, patients, adult, schizophrenia, depression, dsh, male, humans, epidemiology

Identifiers

Local EPrints ID: 62402
URI: http://eprints.soton.ac.uk/id/eprint/62402
ISSN: 0363-0234
PURE UUID: f53c6986-cf45-426d-9db1-c711adbec018
ORCID for Julia Sinclair: ORCID iD orcid.org/0000-0002-1905-2025

Catalogue record

Date deposited: 12 Sep 2008
Last modified: 09 Jan 2022 02:52

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Contributors

Author: Camilla Haw
Author: Keith Hawton
Author: Lesley Sutton
Author: Julia Sinclair ORCID iD
Author: Jonathan Deeks

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