Schizophrenia and deliberate self-harm: a systematic review of risk factors

Haw, Camilla, Hawton, Keith, Sutton, Lesley, Sinclair, Julia and Deeks, Jonathan (2005) Schizophrenia and deliberate self-harm: a systematic review of risk factors Suicide and Life-Threatening Behavior, 35, (1), pp. 50-62. (doi:10.1521/suli.


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Deliberate self-harm (DSH) is a strong predictor of suicide in schizophrenia. The aim of this review was to identify risk factors for DSH in schizophrenia. This systematic review of the international literature examined cohort and case-control studies of patients with schizophrenia or related diagnoses that reported DSH as an outcome. Studies were identified by searching electronic databases and reference lists, and by consulting international experts. Fourteen studies met the eligibility criteria. Of the 29 variables examined by two or more studies, five (past or recent suicidal ideation, previous DSH, past depressive episode, drug abuse or dependence, and higher mean number of psychiatric admissions) were associated with an increased risk of DSH, and one (unemployment) was associated with a reduced risk. Schizophrenic patients with these risk factors need careful follow-up and monitoring, with treatment of any associated comorbid depression or drug abuse. Large, prospective studies of DSH in schizophrenia are needed to further define risk factors and to build on the findings of this review.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1521/suli.
ISSNs: 0363-0234 (print)
Keywords: meta-analysis, prospective studies, risk factors, follow-up studies, treatment, review, research, patients, adult, schizophrenia, depression, dsh, male, humans, epidemiology

ePrint ID: 62402
Date :
Date Event
February 2005Published
Date Deposited: 12 Sep 2008
Last Modified: 16 Apr 2017 17:29
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