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The Montreal Cognitive Assessment: validity and utility in a memory clinic setting

The Montreal Cognitive Assessment: validity and utility in a memory clinic setting
The Montreal Cognitive Assessment: validity and utility in a memory clinic setting
Objective: To prospectively validate the Montreal Cognitive Assessment (MoCA) in a UK memory clinic. Method: We administered the MoCA and Mini-Mental State Examination (MMSE) to 32 subjects fulfilling diagnostic criteria for dementia, to 23 subjects fulfilling diagnostic criteria for mild cognitive impairment (MCI), and to 12 memory clinic comparison subjects, at baseline and then at 6-month follow-up. Clinical diagnoses for dementia and MCI were made according to ICD-10 and Petersen criteria. The sensitivity and specificity of both measures were assessed for detection of MCI and dementia. Results: With a cut-off score of 26, the MMSE had a sensitivity of 17% to detect subjects with MCI, whereas the MoCA detected 83%. The MMSE had a sensitivity of 25% to detect subjects with dementia, whereas the MoCA detected 94%. Specificity for the MMSE was 100%, and specificity for the MoCA was 50%. Of subjects with MCI, 35% developed dementia within 6 months, and all scored less than 26 points on the MoCA at baseline. Conclusions: The MoCA is a useful brief screening tool for the detection of mild dementia or MCI in subjects scoring over 25 points on the MMSE. In patients already diagnosed with MCI, the MoCA helps identify those at risk of developing dementia at 6-month follow-up.
montreal cognitive assessment, alzheimers-disease, mild cognitive impairment, follow-up, impairment, memory, dementia, sensitivity, validity, risk, conversion, mini-mental state examination, mini-mental-state, alzheimer's disease
0706-7437
329-332
Smith, Tasha
a3a1a175-cbf6-46f2-8c4e-3598fa20c0ce
Gildeh, Nadia
02ae8c9f-e8e9-4b21-8515-2b294c4dad80
Holmes, Clive
ada5abf3-8459-4cf7-be40-3f4e9391cc96
Smith, Tasha
a3a1a175-cbf6-46f2-8c4e-3598fa20c0ce
Gildeh, Nadia
02ae8c9f-e8e9-4b21-8515-2b294c4dad80
Holmes, Clive
ada5abf3-8459-4cf7-be40-3f4e9391cc96

Smith, Tasha, Gildeh, Nadia and Holmes, Clive (2007) The Montreal Cognitive Assessment: validity and utility in a memory clinic setting. Canadian Journal of Psychiatry, 52 (5), 329-332.

Record type: Article

Abstract

Objective: To prospectively validate the Montreal Cognitive Assessment (MoCA) in a UK memory clinic. Method: We administered the MoCA and Mini-Mental State Examination (MMSE) to 32 subjects fulfilling diagnostic criteria for dementia, to 23 subjects fulfilling diagnostic criteria for mild cognitive impairment (MCI), and to 12 memory clinic comparison subjects, at baseline and then at 6-month follow-up. Clinical diagnoses for dementia and MCI were made according to ICD-10 and Petersen criteria. The sensitivity and specificity of both measures were assessed for detection of MCI and dementia. Results: With a cut-off score of 26, the MMSE had a sensitivity of 17% to detect subjects with MCI, whereas the MoCA detected 83%. The MMSE had a sensitivity of 25% to detect subjects with dementia, whereas the MoCA detected 94%. Specificity for the MMSE was 100%, and specificity for the MoCA was 50%. Of subjects with MCI, 35% developed dementia within 6 months, and all scored less than 26 points on the MoCA at baseline. Conclusions: The MoCA is a useful brief screening tool for the detection of mild dementia or MCI in subjects scoring over 25 points on the MMSE. In patients already diagnosed with MCI, the MoCA helps identify those at risk of developing dementia at 6-month follow-up.

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More information

Published date: May 2007
Keywords: montreal cognitive assessment, alzheimers-disease, mild cognitive impairment, follow-up, impairment, memory, dementia, sensitivity, validity, risk, conversion, mini-mental state examination, mini-mental-state, alzheimer's disease

Identifiers

Local EPrints ID: 62599
URI: http://eprints.soton.ac.uk/id/eprint/62599
ISSN: 0706-7437
PURE UUID: 39222058-c36c-4b07-acc9-1b6bb5ee06e6
ORCID for Clive Holmes: ORCID iD orcid.org/0000-0003-1999-6912

Catalogue record

Date deposited: 21 Apr 2009
Last modified: 09 Jan 2022 03:00

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Contributors

Author: Tasha Smith
Author: Nadia Gildeh
Author: Clive Holmes ORCID iD

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