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Somatic mutation of genes impacting on the RAS-RAF-MEK-ERK pathway is the most common genetic abnormality in childhood acute lymphoblastic leukaemia, is implicated in disease progression and provides a rationale for therapeutic targeting

Somatic mutation of genes impacting on the RAS-RAF-MEK-ERK pathway is the most common genetic abnormality in childhood acute lymphoblastic leukaemia, is implicated in disease progression and provides a rationale for therapeutic targeting
Somatic mutation of genes impacting on the RAS-RAF-MEK-ERK pathway is the most common genetic abnormality in childhood acute lymphoblastic leukaemia, is implicated in disease progression and provides a rationale for therapeutic targeting
disease, genes, disease progression, time, gene, mutation
0007-1048
p.5
Case, M.
41a17fcd-7227-4523-bbea-786003af2bf3
Matheson, E.
063e772d-b6ed-4c2f-9b62-d91450dae1a6
Minto, L.
d0554de0-c3eb-4471-b477-baf299d5aea4
Hassan, R.
5d00d7c6-0201-4a39-a2d3-a70b1586013d
Harrison, C.
6644a4a5-04dd-4c9b-b2ac-301ef462462c
Bown, N.
77d6f333-a3f1-4245-af94-819b7b8270ff
Bailey, S.
b512093c-6d13-40d0-9e1e-39fd0cd0acb1
Vormoor, J.
7ff99960-2df1-4f3b-a243-a167ab74faf2
Hall, A.
d264326c-a622-4418-b1c4-024867eb9218
Irving, J.
44121f5d-769b-4f17-abd5-11f785f014f8
Case, M.
41a17fcd-7227-4523-bbea-786003af2bf3
Matheson, E.
063e772d-b6ed-4c2f-9b62-d91450dae1a6
Minto, L.
d0554de0-c3eb-4471-b477-baf299d5aea4
Hassan, R.
5d00d7c6-0201-4a39-a2d3-a70b1586013d
Harrison, C.
6644a4a5-04dd-4c9b-b2ac-301ef462462c
Bown, N.
77d6f333-a3f1-4245-af94-819b7b8270ff
Bailey, S.
b512093c-6d13-40d0-9e1e-39fd0cd0acb1
Vormoor, J.
7ff99960-2df1-4f3b-a243-a167ab74faf2
Hall, A.
d264326c-a622-4418-b1c4-024867eb9218
Irving, J.
44121f5d-769b-4f17-abd5-11f785f014f8

Case, M., Matheson, E., Minto, L., Hassan, R., Harrison, C., Bown, N., Bailey, S., Vormoor, J., Hall, A. and Irving, J. (2008) Somatic mutation of genes impacting on the RAS-RAF-MEK-ERK pathway is the most common genetic abnormality in childhood acute lymphoblastic leukaemia, is implicated in disease progression and provides a rationale for therapeutic targeting. British Journal of Haematology, 141 (s1), p.5. (doi:10.1111/j.1365-2141.2008.07061.x).

Record type: Article

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Published date: April 2008
Additional Information: Abstracts of the British Society of Haematology 48th Annual Scientific Meeting, incorporating the 6th Bi-Annual I-BFM Leukaemia Symposium. No. 11.
Keywords: disease, genes, disease progression, time, gene, mutation

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Local EPrints ID: 62699
URI: https://eprints.soton.ac.uk/id/eprint/62699
ISSN: 0007-1048
PURE UUID: d5701ae6-6d97-42cd-a9dd-cd65f823c2d9

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Date deposited: 17 Nov 2008
Last modified: 13 Mar 2019 20:27

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Contributors

Author: M. Case
Author: E. Matheson
Author: L. Minto
Author: R. Hassan
Author: C. Harrison
Author: N. Bown
Author: S. Bailey
Author: J. Vormoor
Author: A. Hall
Author: J. Irving

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