The complex route to MHC class I-peptide complexes


Elliott, T. and Neefjes, J. (2006) The complex route to MHC class I-peptide complexes Cell, 127, (2), pp. 249-251. (doi:10.1016/j.cell.2006.10.001).

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Description/Abstract

The loading of peptides into the groove of MHC class I molecules prior to antigen presentation is a complex process. In this issue of Cell, Park et al. (2006) show that peptide loading gets a helping hand from a resident ER enzyme called protein disulfide isomerase, a chaperone that has oxidoreductase activity

Item Type: Article
Digital Object Identifier (DOI): doi:10.1016/j.cell.2006.10.001
ISSNs: 0092-8674 (print)
Keywords: cell, antigen, loading complex, time, protein, molecules, antigen presentation
Subjects: R Medicine
ePrint ID: 62730
Date :
Date Event
2006Published
Date Deposited: 11 Sep 2008
Last Modified: 16 Apr 2017 17:28
Further Information:Google Scholar
URI: http://eprints.soton.ac.uk/id/eprint/62730

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