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Case series: Adult testicular dermoid tumours - mature teratoma or pre-pubertal teratoma?

Case series: Adult testicular dermoid tumours - mature teratoma or pre-pubertal teratoma?
Case series: Adult testicular dermoid tumours - mature teratoma or pre-pubertal teratoma?
Adult testicular dermoid tumours are rare tumours with no reported potential for recurrent or metastatic spread. Despite this they are currently classified as mature teratoma and managed as if they have equivalent malignant potential. This report describes two cases of adult mature teratoma of dermoid type and questions the classification and pathogenesis of this disease. In one of the cases there was a clear history of a testicular lump arising pre-pubertally, raising the possibility that some adult dermoid tumours may in fact be pre-pubertal teratomas that have persisted into adulthood. Classification as a mature teratoma carries with it a follow-up regimen that includes numerous radiological investigations with their attendant radiation exposure. A positive histological diagnosis and separate classification of adult dermoid tumours would allay clinical fears of recurrence and metastasis and negate the need for repeated radiological investigations
disease, cyst, germ-cell neoplasia, pathogenesis, history, tumours, regimen, follow-up, diagnosis, radiation, mature teratoma, recurrent, pre-pubertal teratoma, testis, classification, time, adult testicular dermoid turnours, primary pure teratoma
0301-1623
643-646
Kendall, T.J.
ca7c0393-cea3-45c6-9f3c-d4c962aba7ba
Featherstone, J.M.
abbcbcea-0954-43fc-850b-04aba2dba056
Mead, G.M.
8a97f978-9c66-4a16-bb03-dd83d20b06a0
Hayes, M.C.
5fc8ef86-8177-4305-ada4-4dd85174ec43
Theaker, J.M.
e24ec934-c79c-471c-8556-d38a15ac845b
Kendall, T.J.
ca7c0393-cea3-45c6-9f3c-d4c962aba7ba
Featherstone, J.M.
abbcbcea-0954-43fc-850b-04aba2dba056
Mead, G.M.
8a97f978-9c66-4a16-bb03-dd83d20b06a0
Hayes, M.C.
5fc8ef86-8177-4305-ada4-4dd85174ec43
Theaker, J.M.
e24ec934-c79c-471c-8556-d38a15ac845b

Kendall, T.J., Featherstone, J.M., Mead, G.M., Hayes, M.C. and Theaker, J.M. (2006) Case series: Adult testicular dermoid tumours - mature teratoma or pre-pubertal teratoma? International Urology and Nephrology, 38 (3-4), 643-646. (doi:10.1007/s11255-005-4984-5).

Record type: Article

Abstract

Adult testicular dermoid tumours are rare tumours with no reported potential for recurrent or metastatic spread. Despite this they are currently classified as mature teratoma and managed as if they have equivalent malignant potential. This report describes two cases of adult mature teratoma of dermoid type and questions the classification and pathogenesis of this disease. In one of the cases there was a clear history of a testicular lump arising pre-pubertally, raising the possibility that some adult dermoid tumours may in fact be pre-pubertal teratomas that have persisted into adulthood. Classification as a mature teratoma carries with it a follow-up regimen that includes numerous radiological investigations with their attendant radiation exposure. A positive histological diagnosis and separate classification of adult dermoid tumours would allay clinical fears of recurrence and metastasis and negate the need for repeated radiological investigations

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More information

Published date: 2006
Keywords: disease, cyst, germ-cell neoplasia, pathogenesis, history, tumours, regimen, follow-up, diagnosis, radiation, mature teratoma, recurrent, pre-pubertal teratoma, testis, classification, time, adult testicular dermoid turnours, primary pure teratoma

Identifiers

Local EPrints ID: 62815
URI: http://eprints.soton.ac.uk/id/eprint/62815
ISSN: 0301-1623
PURE UUID: 59ee8ee0-a706-4b54-b4a4-02570b598cef

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Date deposited: 11 Sep 2008
Last modified: 15 Mar 2024 11:32

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Contributors

Author: T.J. Kendall
Author: J.M. Featherstone
Author: G.M. Mead
Author: M.C. Hayes
Author: J.M. Theaker

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