The University of Southampton
University of Southampton Institutional Repository

The effect of mannitol on renal function after cardiopulmonary bypass in patients with established renal dysfunction

The effect of mannitol on renal function after cardiopulmonary bypass in patients with established renal dysfunction
The effect of mannitol on renal function after cardiopulmonary bypass in patients with established renal dysfunction
The usefulness of mannitol in the priming fluid for cardiopulmonary bypass is uncertain in patients with normal renal function, and has not been studied in patients with established renal dysfunction. We studied 50 patients with serum creatinine between 130 and 250 mu mol.l(-1) having cardiac surgery. Patients were randomised to receive mannitol 0.5 g.kg(-1), or an equivalent volume of Hartmann's solution, in the bypass prime. There were no differences between the groups in plasma creatinine or change in creatinine from baseline, urine output, or fluid balance over the first three postoperative days. We conclude that mannitol has no effect on routine measures of renal function during cardiac surgery in patients with established renal dysfunction
time, failure, management, surgery, serum, dopamine, mortality, risk-factors, patient, prevention, cardiac-surgery
0003-2409
701-704
Smith, M.N.A.
152c8d32-d273-420c-815d-dffd8510293b
Best, D.
ae2bb183-3f74-4933-8c87-123bf62f0e06
Sheppard, S.V.
e1cda445-ccea-4633-a11a-95a28ca31313
Smith, D.C.
217b19f1-7588-4d54-a062-8394eea6dea1
Smith, M.N.A.
152c8d32-d273-420c-815d-dffd8510293b
Best, D.
ae2bb183-3f74-4933-8c87-123bf62f0e06
Sheppard, S.V.
e1cda445-ccea-4633-a11a-95a28ca31313
Smith, D.C.
217b19f1-7588-4d54-a062-8394eea6dea1

Smith, M.N.A., Best, D., Sheppard, S.V. and Smith, D.C. (2008) The effect of mannitol on renal function after cardiopulmonary bypass in patients with established renal dysfunction. Anaesthesia, 63 (7), 701-704. (doi:10.1111/j.1365-2044.2007.05408.x).

Record type: Article

Abstract

The usefulness of mannitol in the priming fluid for cardiopulmonary bypass is uncertain in patients with normal renal function, and has not been studied in patients with established renal dysfunction. We studied 50 patients with serum creatinine between 130 and 250 mu mol.l(-1) having cardiac surgery. Patients were randomised to receive mannitol 0.5 g.kg(-1), or an equivalent volume of Hartmann's solution, in the bypass prime. There were no differences between the groups in plasma creatinine or change in creatinine from baseline, urine output, or fluid balance over the first three postoperative days. We conclude that mannitol has no effect on routine measures of renal function during cardiac surgery in patients with established renal dysfunction

This record has no associated files available for download.

More information

Published date: 2008
Keywords: time, failure, management, surgery, serum, dopamine, mortality, risk-factors, patient, prevention, cardiac-surgery

Identifiers

Local EPrints ID: 62930
URI: http://eprints.soton.ac.uk/id/eprint/62930
ISSN: 0003-2409
PURE UUID: 96c552b8-b272-45d1-b188-7b84e58d3273

Catalogue record

Date deposited: 02 Sep 2008
Last modified: 15 Mar 2024 11:33

Export record

Altmetrics

Contributors

Author: M.N.A. Smith
Author: D. Best
Author: S.V. Sheppard
Author: D.C. Smith

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×