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Guilt, blame and responsibility: men's understanding of their role in the transmission of BRCA1/2 mutations within their family

Hallowell, Nina, Ardern-Jones, Audrey, Eeles, Ros, Foster, Claire L., Lucassen, Anneke, Moynihan, Clare and Watson, Maggie (2006) Guilt, blame and responsibility: men's understanding of their role in the transmission of BRCA1/2 mutations within their family Sociology of Health and Illness, 28, (7), pp. 969-988. (doi:10.1111/j.1467-9566.2006.00515.x). (PMID:17163862).

Record type: Article


Men and women who have a family history of breast and/or ovarian cancer may be offered a predictive genetic test to determine whether or not they carry the family specific BRCA1/2 mutation. The sons and daughters of mutation carriers have a 50 per cent chance of inheriting a mutation, which will increase their risk of developing cancer. Little is known about at-risk men's feelings about the part they play in the transmission of BRCA1/2 mutations within their families. This study investigated high risk men's responses to BRCA1/2 predictive genetic testing. Seventeen in-depth interviews were undertaken with carrier (n= 5) and non-carrier men (n= 12). All men described genetic testing as a familial duty. It is observed that carriers and non-carriers mobilised differing explanations about their role in the aetiology of risk. It is noted that men engage in a form of narrative reconstruction in which they draw upon discourses of guilt and blame or fate and predestiny in an effort to present themselves as morally responsible or blameless. It is argued that narrative reconstruction enables these men to reconcile their genetic identity, self and family.

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Published date: November 2006
Keywords: men, genetic testing, breast cancer, responsibility, narrative reconstruction
Organisations: Faculty of Health Sciences


Local EPrints ID: 63987
ISSN: 0141-9889
PURE UUID: 71a84612-46ee-45c0-a4eb-d2b0a8511b18
ORCID for Claire L. Foster: ORCID iD

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Date deposited: 21 Nov 2008
Last modified: 17 Jul 2017 14:14

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Author: Nina Hallowell
Author: Audrey Ardern-Jones
Author: Ros Eeles
Author: Anneke Lucassen
Author: Clare Moynihan
Author: Maggie Watson

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