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The fabrication of lab-on-chip devices from fluoropolymers

The fabrication of lab-on-chip devices from fluoropolymers
The fabrication of lab-on-chip devices from fluoropolymers
Three different rapid manufacturing methods for the construction of fluoropolymer microfluidic devices were investigated: (1) fluoropolymer/epoxy laminate/fluoropolymer structures, (2) fluoropolymer/fluoropolymer structures and (3) fluoropolymer/epoxy laminate/glass structures. The structures are chemically and physically robust and the fluoropolymer constructs can be used for optical wave guiding. Principles behind the use of fluoropolymer waveguide constructs and a basic theoretical analysis of the improvements they offer are presented. The otherwise problematic bonding of the polymers was facilitated by chemical (sodium naphthalene) surface treatment. The effects of the process were characterized by contact angle and bond strength measurements. For demonstration purposes, microfluidic channels were fabricated using Ordyl SY epoxy laminate (methods 1 and 3) and hot embossing of the polymers (method 2). The first method (fluoropolymer/epoxy laminate/fluoropolymer) proved to be the most reliable and successful, in particular when bonding the various layers. (Some figures in this article are in colour only in the electronic version)
0960-1317
064011-[8pp]
Taberham, A.
51b87dd3-532f-43b8-a469-d01cee1f4829
Kraft, M.
54927621-738f-4d40-af56-a027f686b59f
Mowlem, M.
6f633ca2-298f-48ee-a025-ce52dd62124f
Morgan, H.
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Taberham, A.
51b87dd3-532f-43b8-a469-d01cee1f4829
Kraft, M.
54927621-738f-4d40-af56-a027f686b59f
Mowlem, M.
6f633ca2-298f-48ee-a025-ce52dd62124f
Morgan, H.
de00d59f-a5a2-48c4-a99a-1d5dd7854174

Taberham, A., Kraft, M., Mowlem, M. and Morgan, H. (2008) The fabrication of lab-on-chip devices from fluoropolymers. Journal of Micromechanics and Microengineering, 18 (6), 064011-[8pp]. (doi:10.1088/0960-1317/18/6/064011).

Record type: Article

Abstract

Three different rapid manufacturing methods for the construction of fluoropolymer microfluidic devices were investigated: (1) fluoropolymer/epoxy laminate/fluoropolymer structures, (2) fluoropolymer/fluoropolymer structures and (3) fluoropolymer/epoxy laminate/glass structures. The structures are chemically and physically robust and the fluoropolymer constructs can be used for optical wave guiding. Principles behind the use of fluoropolymer waveguide constructs and a basic theoretical analysis of the improvements they offer are presented. The otherwise problematic bonding of the polymers was facilitated by chemical (sodium naphthalene) surface treatment. The effects of the process were characterized by contact angle and bond strength measurements. For demonstration purposes, microfluidic channels were fabricated using Ordyl SY epoxy laminate (methods 1 and 3) and hot embossing of the polymers (method 2). The first method (fluoropolymer/epoxy laminate/fluoropolymer) proved to be the most reliable and successful, in particular when bonding the various layers. (Some figures in this article are in colour only in the electronic version)

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Published date: 2008

Identifiers

Local EPrints ID: 64297
URI: https://eprints.soton.ac.uk/id/eprint/64297
ISSN: 0960-1317
PURE UUID: 263cbd4e-ef7b-4577-9697-c3b22a99228e
ORCID for H. Morgan: ORCID iD orcid.org/0000-0003-4850-5676

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Date deposited: 08 Dec 2008
Last modified: 10 Sep 2019 00:45

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Contributors

Author: A. Taberham
Author: M. Kraft
Author: M. Mowlem
Author: H. Morgan ORCID iD

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