Failure of elimination of amyloid-beta from the brain in Alzheimer's disease


de Silva, Prasanna, Carare, Roxana O. and Weller, Roy O. (2008) Failure of elimination of amyloid-beta from the brain in Alzheimer's disease Progress in Neurology and Psychiatry, 12, (4), pp. 6-10. (doi:10.1002/pnp.72).

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Description/Abstract

Accumulation of amyloid-beta (A-beta) in the brain is a major cause of dementia in Alzheimer's disease.I n this article, Dr de Silva, Dr Carare and ProfessorWeller review the mechanisms for the elimination of A-beta from the brain, the reasons why these mechanisms fail in Alzheimer's disease, and how understanding this failure may lead to new approaches to the treatment of Alzheimer's disease.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1002/pnp.72
ISSNs: 1367-7543 (print)
Subjects:
ePrint ID: 66621
Date :
Date Event
May 2008Published
Date Deposited: 02 Jul 2009
Last Modified: 18 Apr 2017 21:33
Further Information:Google Scholar
URI: http://eprints.soton.ac.uk/id/eprint/66621

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