Hyperplastic polyps of the duodenum: an unusual histological finding
Hyperplastic polyps of the duodenum: an unusual histological finding
A 58-year-old man underwent upper gastrointestinal surveillance endoscopy for Barrett’s oesophagus. This showed a possible gastric ulcer, although histological examination was normal. Follow-up endoscopy showed white ridges in the distal duodenum and these were subjected to biopsy. Histological examination of the biopsy specimens showed polypoid duodenal mucosa showing features similar to those of a hyperplastic polyp of the colon. In addition, the mucosal surface was focally of gastric surface type. The features were interpreted overall as most likely to represent an unusual form of regenerative change in the setting of previous chronic inflammatory mucosal damage. The case is presented as an unusual histological phenomenon at this site; it would be important not to overdiagnose neoplasia in this situation.
1305-1306
Roche, H.J.
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Carr, N.J.
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Laing, H.
4a887014-9e25-4aea-ad7a-415e7a2d3200
Bateman, A.C.
4e97a5ca-662c-451d-bdb3-33f35420ceed
2006
Roche, H.J.
d752c092-56dc-4fdc-825f-8805a859997a
Carr, N.J.
810e44dc-90d5-496c-85b6-6b2fa1c07dd7
Laing, H.
4a887014-9e25-4aea-ad7a-415e7a2d3200
Bateman, A.C.
4e97a5ca-662c-451d-bdb3-33f35420ceed
Roche, H.J., Carr, N.J., Laing, H. and Bateman, A.C.
(2006)
Hyperplastic polyps of the duodenum: an unusual histological finding.
Journal of Clinical Pathology, 59, .
(doi:10.1136/jcp.2005.035022).
Abstract
A 58-year-old man underwent upper gastrointestinal surveillance endoscopy for Barrett’s oesophagus. This showed a possible gastric ulcer, although histological examination was normal. Follow-up endoscopy showed white ridges in the distal duodenum and these were subjected to biopsy. Histological examination of the biopsy specimens showed polypoid duodenal mucosa showing features similar to those of a hyperplastic polyp of the colon. In addition, the mucosal surface was focally of gastric surface type. The features were interpreted overall as most likely to represent an unusual form of regenerative change in the setting of previous chronic inflammatory mucosal damage. The case is presented as an unusual histological phenomenon at this site; it would be important not to overdiagnose neoplasia in this situation.
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Published date: 2006
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Local EPrints ID: 67541
URI: http://eprints.soton.ac.uk/id/eprint/67541
ISSN: 0021-9746
PURE UUID: 241c2826-6f94-41b3-839e-e1a6586b4f51
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Date deposited: 24 Aug 2009
Last modified: 13 Mar 2024 18:53
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Author:
H.J. Roche
Author:
N.J. Carr
Author:
H. Laing
Author:
A.C. Bateman
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