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An enantioselective synthesis of carbafuranose sugars based on a linchpin carbacyclisation approach

An enantioselective synthesis of carbafuranose sugars based on a linchpin carbacyclisation approach
An enantioselective synthesis of carbafuranose sugars based on a linchpin carbacyclisation approach
Enantiopure carbafuranose derivatives were synthesised via a linchpin carbacyclisation process starting from 1,4-bisepoxides. Both 2-deoxy and 2-deoxy-6-hydroxycarbafuranose derivatives were obtained, which were converted to suitably protected precursors for carbanucleoside synthesis.
0957-4166
821-831
Leung, Leo M.H.
c5dca465-0459-416b-8713-ef0ff4f659fd
Light, Mark E.
cf57314e-6856-491b-a8d2-2dffc452e161
Gibson, Vicky
c2078543-eead-4d7e-9e4b-be193c78f09e
Linclau, Bruno
19b9cacd-b8e8-4c65-af36-6352cade84ba
Leung, Leo M.H.
c5dca465-0459-416b-8713-ef0ff4f659fd
Light, Mark E.
cf57314e-6856-491b-a8d2-2dffc452e161
Gibson, Vicky
c2078543-eead-4d7e-9e4b-be193c78f09e
Linclau, Bruno
19b9cacd-b8e8-4c65-af36-6352cade84ba

Leung, Leo M.H., Light, Mark E., Gibson, Vicky and Linclau, Bruno (2009) An enantioselective synthesis of carbafuranose sugars based on a linchpin carbacyclisation approach. [in special issue: Celebration of the 65th Birthday of Professor George Flee] Tetrahedron: Asymmetry, 20 (6-8), 821-831. (doi:10.1016/j.tetasy.2009.02.019).

Record type: Article

Abstract

Enantiopure carbafuranose derivatives were synthesised via a linchpin carbacyclisation process starting from 1,4-bisepoxides. Both 2-deoxy and 2-deoxy-6-hydroxycarbafuranose derivatives were obtained, which were converted to suitably protected precursors for carbanucleoside synthesis.

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More information

Published date: 7 May 2009
Additional Information: Dedicated to Professor George Fleet on the occasion of his 65th birthday.
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Identifiers

Local EPrints ID: 67648
URI: http://eprints.soton.ac.uk/id/eprint/67648
DOI: doi:10.1016/j.tetasy.2009.02.019
ISSN: 0957-4166
PURE UUID: d653dff6-ad85-49fb-ba7d-e10dee519f9c
ORCID for Mark E. Light: ORCID iD orcid.org/0000-0002-0585-0843
ORCID for Bruno Linclau: ORCID iD orcid.org/0000-0001-8762-0170

Catalogue record

Date deposited: 02 Sep 2009
Last modified: 14 Mar 2024 02:44

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Contributors

Author: Leo M.H. Leung
Author: Mark E. Light ORCID iD
Author: Vicky Gibson
Author: Bruno Linclau ORCID iD

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